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Malignant neoplasms of vulva

International Classification of Diseases for Mortality and Morbidity Statistics, 11th Revision, v2024-01

Squamous cell carcinoma of the vulva occurs predominantly in the older age group. Although the incidence rate of vulvar intraepithelial neoplasia is increasing, that of squamous cell carcinoma of the vulva is declining, reflecting earlier detection and more successful treatment. In addition to human papillomavirus infection, cigarette smoking is a putative risk factor for vulvar squamous cell carcinoma. There are three known precursor lesions: vulvar intraepithelial neoplasia, lichen sclerosus and chronic granulomatous disease. Other important epithelial malignancies of the vulva are Paget disease and Bartholin gland carcinoma. They are much less common than squamous lesions, and the risk factors are largely unknown. Prominent non-epithelial tumours are malignant melanoma and sarcoma botryoides.

exclusions

• Malignant mesenchymal neoplasms  (2B50-2B5Z)

sections/codes in this section (2C70-2C70)

• Basal cell carcinoma of vulva  (2C70.0)
• Melanoma of vulva  (2C70.1)
• Squamous cell carcinoma of vulva  (2C70.2)
• Other specified malignant neoplasms of vulva  (2C70.Y)
• Malignant neoplasms of vulva, unspecified  (2C70.Z)

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