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Immunodeficiency-associated lymphoproliferative disorders

International Classification of Diseases for Mortality and Morbidity Statistics, 11th Revision, v2024-01

Post-transplant lymphoproliferative disorder (PTLD) is a polyclonal (benign) or clonal (malignant) proliferation of lymphoid cells that develops as a consequence of immunosuppression in a recipient of a solid organ or bone marrow allograft. PTLDs comprise a spectrum ranging from early, Epstein-Barr virus (EBV)-driven polyclonal lymphoid proliferations to EBV-positive or EBV-negative lymphomas of predominantly B-cell or less often T-cell type. In other immunodeficiency-associated lymphoproliferative disorders, association with EBV is less pronounced.

sections/codes in this section (2B32-2B32)

• Post-transplant lymphoproliferative disorder, early lesion  (2B32.0)
• Reactive plasmacytic hyperplasia  (2B32.1)
• Post-transplant lymphoproliferative disorder, Infectious mononucleosis-like  (2B32.2)
• Polymorphic post-transplant lymphoproliferative disorder  (2B32.3)
• Other specified immunodeficiency-associated lymphoproliferative disorders  (2B32.Y)
• Immunodeficiency-associated lymphoproliferative disorders, unspecified  (2B32.Z)

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