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Klinefelter syndrome

International Classification of Diseases for Mortality and Morbidity Statistics, 11th Revision, v2024-01

Klinefelter syndrome defines a group of chromosomal disorders in which there is at least one extra X chromosome compared with the normal 46,XY male karyotype. The effects on physical features and on physical and cognitive development increase with the number of extra X's, and each extra X is associated with an intelligence quotient (IQ) decrease of approximately 15-16 points, with language most affected, particularly expressive language skills.

sections/codes in this section (LD50.3-LD50.3)

• Klinefelter syndrome with karyotype 47,XXY, regular  (LD50.30)
• Klinefelter syndrome, male with more than two X chromosomes  (LD50.31)
• Other specified Klinefelter syndrome  (LD50.3Y)
• Klinefelter syndrome, unspecified  (LD50.3Z)

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