ICD-11 MMS

02 Neoplasms

In situ neoplasms, except of lymphoid, haematopoietic, central nervous system or related tissues  (2E60-2E6Z)

2E64 Carcinoma in situ of skin

Intraepidermal squamous cell carcinoma

International Classification of Diseases for Mortality and Morbidity Statistics, 11th Revision, v2024-01


Malignant squamous neoplasia confined to the epidermis of extragenital skin and known commonly as Bowen disease. It arises most frequently on chronically sun-exposed glabrous skin of the head and neck or lower legs. It typically presents as single or multiple well-demarcated scaly erythematous patches, nodules or plaques which histologically show extensive keratinocytic atypia. It may develop from preexisting actinic keratosis (Actinic intraepidermal squamous cell carcinoma). Although it is most commonly associated with exposure to ultraviolet radiation, other carcinogens such as arsenic and tar may be implicated. Human papilloma virus may represent an additional risk factor in immunosuppressed patients.

sections/codes in this section (2E64.0-2E64.0)

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