Gastrointestinal stromal tumour, primary site

International Classification of Diseases for Mortality and Morbidity Statistics, 11th Revision, v2024-01


This is the most common mesenchymal tumour that arises in the gastrointestinal tract. It is generally immunohistochemically positive for CD117 (KIT), phenotypically paralleling Cajal-cell differentiation, and most examples contain KIT- or PDGFRA-activating mutations. It is most frequent in the stomach and to a lesser degree in the small intestine. The prognosis depends on the tumour size and the mitotic activity.

sections/codes in this section (2B5B-2B5B)

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