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2C90 Malignant neoplasms of kidney, except renal pelvis International Classification of Diseases for Mortality and Morbidity Statistics, 11th Revision, v2024-01 Cancer of the kidney amounts to 2% of the total human cancer burden, with approximately 190,000 new cases diagnosed each year. They occur in all world regions, with a preference for developed countries. Etiological factors include environmental carcinogens (tobacco smoking) and lifestyle factors, in particular obesity. Although renal tumours can be completely removed surgically, haematogeneous metastasis is frequent and may occur already at an early stage of the disease. The pattern of somatic mutations in kidney tumours has been extensively investigated and has become, in addition to histopathology, a major criterion for classification. Kidney tumours also occur in the setting of several inherited cancer syndromes, including von Hippel-Lindau disease.
exclusions sections/codes in this section (2C90-2C90) postcoordination Add Stem and/or Extension codes to form a cluster code which adds detail to the condition.
Laterality - only one may be selected [select] XK9J Bilateral XK8G Left XK9K Right XK70 Unilateral, unspecified Specific anatomy - multiple selections are allowed [select] XA5EP6 Renal capsule XA35W4 Renal cortex XA91E4 Renal medulla – XA9Q52 Renal pyramid XA4UD2 Renal hilum XA40R2 Glomerulus – XA8AN8 Nephron – XA2364 Renal tubule XA6KU8 Kidney XA5EP6 Renal capsule XA35W4 Renal cortex XA91E4 Renal medulla – XA9Q52 Renal pyramid XA21J4 Renal pelvis – XA0AC1 Renal calyces –– XA6N83 Major calyx –– XA8XL0 Minor calyx – XA7NQ9 Ureteropelvic junction XA4UD2 Renal hilum XA40R2 Glomerulus – XA8AN8 Nephron – XA2364 Renal tubule Histopathology - only one may be selected [select] XH2ZQ0 Adenocarcinoma with mixed subtypes XH0349 Adenocarcinoma, intestinal type XH8B45 Solid carcinoma, NOS XH8DS0 Neuroendocrine tumour, NOS XH8LX8 Neuroendocrine carcinoma, low grade XH55D7 Neuroendocrine carcinoma, well-differentiated XH9LV8 Neuroendocrine tumor, grade 1 XH7NM1 Enterochromaffin cell carcinoid XH0U20 Neuroendocrine carcinoma, NOS XH7F73 Neuroendocrine carcinoma, moderately differentiated XH24W2 Lepidic adenocarcinoma XH3QM0 Minimally invasive adenocarcinoma, Non-mucinous XH4302 Adenoid cystic carcinoma XH2098 Minimally invasive adenocarcinoma, Mucinous XH6LV9 Papillary adenocarcinoma, NOS XH95U1 Villoglandular carcinoma XH6QG3 Micropapillary carcinoma, NOS XH4MW7 Micropapillary adenocarcinoma XH7KL6 Pituitary carcinoma, NOS XH6L02 Clear cell adenocarcinoma, NOS XH5085 Hereditary leiomyomatosis and renal cell carcinoma (HLRCC) syndrome-associated renal cell carcinoma XH1442 MiT Family translocation carcinomas XH8EN1 Succinate dehydrogenase deficient renal cell carcinoma XH07X3 Alveolar adenocarcinoma XH05V6 Renal cell carcinoma, NOS XH3Z08 Renal cell carcinoma, unclassified XH0RU3 Acquired cystic disease associated renal cell carcinoma XH7K79 Tubulocystic renal cell carcinoma XH1VB1 Hybrid oncocytic chromophobe tumour XH3Z50 Follicular carcinoma, NOS XH9508 Endometrioid adenocarcinoma, ciliated cell variant XH0718 Endometrioid adenocarcinoma, secretory variant XH4KH2 Adrenal cortical carcinoma XH0SD2 Endometrioid adenocarcinoma, NOS XH51K1 Neuroendocrine tumour, grade 2 XH09B7 Endometrioid cystadenocarcinoma XH6KR7 Endometrioid adenofibroma, malignant XH0GS9 Adenocarcinoma, endocervical type XH8SF8 Islet cell adenomatosis XH43E4 Perihilar cholangiocarcinoma XH4BY1 Islet cell adenoma XH3CU4 Villoglandular variant of endometrioid adenocarcinoma XH5QV8 Pituitary blastoma XH0Y80 Follicular carcinoma, encapsulated, angioinvasive XH46F1 Clear cell renal cell carcinoma, NOS XH9SA7 Basal cell adenocarcinoma XH85C2 Endolymphatic sac tumor XH4PB1 Acinar adenocarcinoma of prostate XH8E54 Mixed neuroendocrine non-neuroendocrine neoplasm (MiNEN) XH5QW8 Neuroendocrine tumour, grade 3 XH1NL5 Nesidioblastoma XH5XB7 Islet cell carcinoma XH2ST7 Islet cell tumor, NOS XH4SH8 Insulinoma, NOS XH93H8 Gastrinoma XH7JQ0 Parathyroid carcinoma XH9LV7 Basophil carcinoma XH7152 Glucagon-like peptide-producing tumour XH7LW9 L-cell tumour XH9ZS8 Pancreatic peptide and pancreatic peptide-like peptide within terminal tyrosine amide producing tumour XH4NQ8 Glucagonoma XH2PF0 Enteroglucagonoma XH72E5 Vipoma XH5VH0 Somatostatinoma XH41P2 Endocrine tumour, functioning, NOS XH7AG8 ACTH-producing tumour XH60V1 Medullary thyroid carcinoma XH3BU6 Bile duct cystadenocarcinoma XH2MW1 Medullary carcinoma with amyloid stroma XH8VU6 Poorly differentiated thyroid carcinoma XH4NH4 Pituitary neuroendocrine tumour XH2ZA2 Bronchial adenoma, carcinoid XH5TR7 Adenocarcinoma of lung, mixed mucinous and non-mucinous XH7GY6 Adenocarcinoma of lung, mucinous XH2035 Bronchiolo-alveolar carcinoma, non-mucinous XH6LF9 Carcinoma simplex XH0XL5 Carcinoma, diffuse type XH7M15 Cholangiocarcinoma XH7SS7 Chromophobe carcinoma XH2Q13 Clear cell adenocarcinofibroma XH6YS0 Clear cell adenocarcinoma, mesonephroid XH4SQ4 Collecting duct carcinoma XH7QJ6 Combined hepatocellular carcinoma and cholangiocarcinoma XH4KK0 Cyst-associated renal cell carcinoma XH0LH8 Enterochromaffin-like cell tumour XH5P16 Fetal adenocarcinoma XH7TE3 Follicular adenocarcinoma, moderately differentiated XH0VD1 Follicular adenocarcinoma, trabecular XH8FK7 Follicular adenocarcinoma, well differentiated XH3DN7 Follicular carcinoma, minimally invasive XH90N9 Follicular carcinoma, oxyphilic cell XH3XT5 Glycogen-rich carcinoma XH4262 Goblet cell carcinoid XH2EH4 Granular cell carcinoma XH4T58 Hepatocellular carcinoma, clear cell type XH9Q35 Hepatocellular carcinoma, fibrolamellar XH0G90 Hepatocellular carcinoma, pleomorphic type XH5761 Hepatocellular carcinoma, scirrhous XH3T17 Hepatocellular carcinoma, spindle cell variant XH6YH5 Hurthle cell adenocarcinoma XH8MQ3 Hurthle cell carcinoma XH8WM4 Linitis plastica XH6TK0 Lipid-rich carcinoma XH81N8 Merkel cell carcinoma XH7019 Mixed acidophil-basophil carcinoma XH8EZ3 Mixed acinar-endocrine carcinoma XH74Y9 Mixed acinar-endocrine-ductal carcinoma XH6H10 Mixed adenoneuroendocrine carcinoma XH2AM6 Mixed cell adenocarcinoma XH7CY5 Mixed ductal-endocrine carcinoma XH6UP4 Mixed endocrine and exocrine adenocarcinoma XH7DG7 Mixed medullary-follicular carcinoma XH3340 Mixed medullary-papillary carcinoma XH9LZ7 Mixed pancreatic endocrine and exocrine tumour, malignant XH1108 Nonencapsulated sclerosing carcinoma XH09D6 Oxyphilic adenocarcinoma XH3614 Islet cell adenocarcinoma XH3709 Pancreatic neuroendocrine tumor, nonfunctioning XH6XY9 Pancreatobiliary-type carcinoma XH1ND9 Papillary carcinoma of thyroid XH85E5 Papillary carcinoma, columnar cell XH0426 Papillary carcinoma, diffuse sclerosing XH0Q59 Papillary carcinoma, encapsulated, of thyroid XH29M4 Papillary carcinoma, follicular variant XH5YT2 Papillary carcinoma, oncocytic variant XH2AW7 Papillary microcarcinoma XH1D07 Papillary renal cell carcinoma XH4Q20 Papillotubular adenocarcinoma XH1JZ0 Parietal cell carcinoma XH6153 Renal cell carcinoma, chromophobe type XH9DH7 Renal cell carcinoma, sarcomatoid XH4FS4 Scirrhous adenocarcinoma XH34G3 Solid carcinoma with mucin formation XH0JE3 Superficial spreading adenocarcinoma XH7EX3 Trabecular adenocarcinoma XH4TA4 Tubular adenocarcinoma XH1Z69 Typical carcinoid XH22Z8 Carcinoma of Skene, Cowper and Littre Glands XH0X20 Villous adenocarcinoma XH0A57 Water-clear cell adenocarcinoma XH8UE4 Adenocarcinoma, metastatic, NOS XH4ZC3 Basal cell carcinoma of the prostate XH4W48 Hepatocellular carcinoma, NOS XH81Q9 Bronchial adenoma, cylindroid XH92Y9 Thymic carcinoma with adenoid cystic carcinoma-like features XH1YZ3 Cribriform carcinoma, NOS XH4YG1 Cribriform comedo-type carcinoma XH74B2 Serrated adenocarcinoma XH2QZ6 Acidophil carcinoma XH5LA4 Adenocarcinoid tumour XH74S1 Adenocarcinoma, NOS XH7QZ0 Adenocarcinoma in adenomatous polyp XH2ZH8 Adenocarcinoma in adenomatous polyposis coli XH9YR3 Adenocarcinoma in multiple adenomatous polyps XH7QB1 Adenocarcinoma in tubulovillous adenoma XH6DA5 Adenocarcinoma in villous adenoma XH5RE1 Adenocarcinoma of anal glands Has manifestation - multiple selections are allowed [select] MG30.10 Chronic cancer pain Has severity - only one may be selected [select] XS1G Stage I XS4P Stage II XS6H Stage III XS9R Stage IV Has alternative severity1 - only one may be selected [select] XS56 Grade I XS58 Grade II XS7Z Grade III XS7M Grade IV XS7H Undetermined grade Has alternative severity2 - only one may be selected [select] XS0J A Remission / Free of disease XS05 B Local Disease – XS0E Local limited – XS67 Locally advanced XS9S C Regional disease XS4Z D Distant disease
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