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ED51.00 Benign acanthosis nigricans

International Classification of Diseases for Mortality and Morbidity Statistics, 11th Revision, v2024-01

Benign acanthosis nigricans is a thickening and pigmentation affecting predominantly flexural skin, especially the neck, axillae and groins. It is thought to be due to high concentrations of insulin binding to insulin-like growth factor receptors, with resultant keratinocyte proliferation. It is strongly associated with insulin resistance and obesity. Type 2 diabetes and the metabolic syndrome are commonly associated.

exclusions

• Paraneoplastic acanthosis nigricans  (EL10)

synonyms

• Benign acanthosis nigricans
• Acanthosis nigricans associated with Type II diabetes and obesity

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