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CB22.0 Fibrosing mediastinitis

International Classification of Diseases for Mortality and Morbidity Statistics, 11th Revision, v2024-01

Fibrosing mediastinitis, also known as sclerosing mediastinitis or mediastinal fibrosis, is a disorder characterised by an excessive fibrotic reaction in the mediastinum. It can result in compromise of airways, great vessels, and other mediastinal structures, with morbidity directly related to the location and extent of fibrosis. The commonest cause is histoplasmosis, of which it is a rare late complication, but it may also occur in association with other infections and with systemic autoimmune disorders such as Behçet disease, granulomatosis with polyangiitis and retroperitoneal fibrosis.

synonyms

• Fibrosing mediastinitis
• mediastinal fibrosis
• idiopathic mediastinal fibrosis
• Histoplasmosis-related fibrosing mediastinitis
• Histoplasmosis-related mediastinal fibrosis mediastinitis
• Fibrosing mediastinitis in association with systemic autoimmune disease
• Idiopathic hilar fibrosis

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