6C43.3 Opioid intoxication International Classification of Diseases for Mortality and Morbidity Statistics, 11th Revision, v2024-01 Opioid intoxication is a clinically significant transient condition that develops during or shortly after the consumption of opioids that is characterised by disturbances in consciousness, cognition, perception, affect, behaviour, or coordination. These disturbances are caused by the known pharmacological effects of opioids and their intensity is closely related to the amount of opioids consumed. They are time-limited and abate as opioids are cleared from the body. Presenting features may include somnolence, stupor, mood changes (e.g. euphoria followed by apathy and dysphoria), psychomotor retardation, impaired judgment, respiratory depression, slurred speech, and impairment of memory and attention. In severe intoxication coma may ensue. A characteristic physical sign is pupillary constriction but this sign may be absent when intoxication is due to synthetic opioids. Severe opioid intoxication can lead to death due to respiratory depression.
exclusions postcoordination Add Stem and/or Extension codes to form a cluster code which adds detail to the condition.
Medication - multiple selections are allowed [select] XM3473 Hydromorphinol XM8SD7 Hydromorphone XM78E0 Metopon XM7VL7 Morpholinylethylmorphine XM7W06 Nicomorphine XM9BE3 Normorphine XM64M0 Oxymorphone XM1KZ5 Morphine XM0P98 Benzylmorphine XM7ZJ1 Myrophine XM4ES0 Opium XM2T93 Opium alkaloids (total) XM69X3 Opium alkaloids standardized powdered XM91H1 Opium alkaloids tincture (camphorated) XM1EE2 Laudanum XM1YK2 Papaveretum XM1LB8 Paregoric XM4SL9 Oxycodone XM79K2 Acetyldihydrocodeinone XM7HX3 Eucodal XM9UH3 Nalfurafine XM4587 Codeine, codeine derivatives and other opioids used in cough suppression XM3DS6 Acetyldihydrocodeine XM05R0 Antitussive codeine mixture XM3YP8 Cliradon XM4046 Desocodeine XM06K5 Dihydrocodeine XM77C9 Dihydroisocodeine XM9UN6 Hycodan XM0YG5 Hydroxydihydrocodeinone XM07U7 Percodan XM5NP7 Piminodine XM3WN9 Ethylmorphine XM8E09 Hydrocodone XM6RX7 Noscapine XM4QV7 Pholcodine XM9UV0 Dextromethorphan XM2358 Thebacon XM7V96 Dimemorfan XM5PZ4 Normethadone XM1ZY9 Methadone, methadone derivatives and other drugs used to treat opioid addictive disorders XM7XP1 Methadone – XM9RG7 Levo-iso-methadone XM4MV8 Opioid anaesthetics XM4G88 Alfentanil XM1EF3 Sufentanil XM7YQ6 Anileridine XM0YQ0 Remifentanil XM7TT0 Antagonist narcotic analgesic XM0850 Cyclazocine XM65J2 Levallorphan XM4HP3 Morphine antagonist XM14T9 Naloxone XM2M16 Naltrexone XM9BM4 Narcotic antagonist XM5DJ2 Opiate antagonists XM3TK0 Methylnaltrexone bromide XM4GP3 Alvimopan XM93Z3 Naloxegol XM6KY8 Opioid antagonist XM4S22 Other opioid analgesics, natural, synthetic and semi-synthetic XM30T6 Prodine XM9907 Antitussive opiate XM6C31 Cough mixture containing opiates XM8ZF5 Dextrorphan XM1K75 Difencloxazine XM1HE9 Dilaudid XM9SW6 Dipipanone XM81P5 Dromoran XM4EW3 Eptazocine XM6CK0 Ethoheptazine XM35C1 Heptalgin XM5F21 Levo-dromoran XM4P40 Levopropoxyphene XM1R71 Levorphanol XM0GS3 Meperidine XM8PP7 Narcotic synthetic XM8MP5 Nisentil XM7S23 Opioid XM04Z5 Phenadoxone XM2542 Phenazocine XM9B34 Phenomorphan XM72D5 Pipadone XM39L3 Profadol XM9AZ5 Promedol XM3E08 Propoxyphene XM6625 Racemoramide XM8804 Thebaine XM09H6 Tilidine XM7KC0 Tramadol XM5UK3 Viminol XM9Y28 Diphenoxylate XM86N4 Loperamide XM9NL3 Phenylpiperidine derivatives – XM9HP7 Ketobemidone – XM76M8 Fentanyl XM8286 Diphenylpropylamine derivatives – XM3246 Dextromoramide – XM55Z5 Piritramide – XM8GB8 Dextropropoxyphene – XM5GN5 Bezitramide XM1QE0 Benzomorphan derivatives – XM9K14 Pentazocine XM09R6 Morphinan derivatives – XM1682 Butorphanol – XM4P05 Nalbuphine XM9Z94 Buprenorphine XM02X7 Etorphine XM3PK7 Acetorphine XM0K66 Phenoperidine XM40T9 Meptazinol XM0GU8 Drotebanol XM7VK6 Loperamide oxide XM13Q9 Dezocine XM25Z3 Tapentadol XM1G85 Oliceridine XM4PD9 Nalmefene XM4M74 Difelikefalin XM05B3 Diamorphine XM69R4 Morphine, morphine derivatives and metabolites XM39E2 14-hydroxydihydro-morphinone XM5CY8 Acemorphan XM0E25 Benzomorphan XM8YM7 Benzyl morphine XM0BB1 Blue velvet XM45R8 Desomorphine XM4T95 Dihydromorphine Associated with - multiple selections are allowed [select] PB20 Unintentional exposure to or harmful effects of opioids or related analgesics PB21 Unintentional exposure to or harmful effects of sedative hypnotic drugs or other CNS depressants PB22 Unintentional exposure to or harmful effects of psychostimulants PB23 Unintentional exposure to or harmful effects of cannabinoids or hallucinogens PB24 Unintentional exposure to or harmful effects of analgesics, antipyretics or nonsteroidal anti-inflammatory drugs PB25 Unintentional exposure to or harmful effects of antidepressants PB26 Unintentional exposure to or harmful effects of antipsychotics PB27 Unintentional exposure to or harmful effects of antiepileptics or antiparkinsonism drugs PB28 Unintentional exposure to or harmful effects of other or unspecified drug, medicament or biological substance PB29 Unintentional exposure to or harmful effects of multiple drugs, medicaments or biological substances PB30 Unintentional exposure to or harmful effects of alcohols PB31 Unintentional exposure to or harmful effects of organic solvents PB32 Unintentional exposure to or harmful effects of carbon monoxide PB33 Unintentional exposure to or harmful effects of pesticides PB34 Unintentional exposure to or harmful effects of corrosive substances PB35 Unintentional exposure to or harmful effects of halogen derivatives of aliphatic or aromatic hydrocarbons PB36 Unintentional exposure to or harmful effects of other or unspecified substances chiefly nonmedicinal as to source PC90 Intentional self-harm by exposure to or harmful effects of opioids or related analgesics PC91 Intentional self-harm by exposure to or harmful effects of sedative hypnotic drugs or other CNS depressants PC92 Intentional self-harm by exposure to or harmful effects of psychostimulants PC93 Intentional self-harm by exposure to or harmful effects of cannabinoids or hallucinogens PC94 Intentional self-harm by exposure to or harmful effects of analgesics, antipyretics or nonsteroidal anti-inflammatory drugs PC95 Intentional self-harm by exposure to or harmful effects of antidepressants PC96 Intentional self-harm by exposure to or harmful effects of antipsychotics PC97 Intentional self-harm by exposure to or harmful effects of antiepileptics or antiparkinsonism drugs PC98 Intentional self-harm by exposure to other and unspecified drug, medicament and biological substance PC99 Intentional self-harm by exposure to or harmful effects of multiple drugs, medicaments or biological substances PD00 Intentional self-harm by exposure to or harmful effects of alcohols PD01 Intentional self-harm by exposure to or harmful effects of organic solvents PD02 Intentional self-harm by exposure to or harmful effects of carbon monoxide PD03 Intentional self-harm by exposure to or harmful effects of pesticides PD04 Intentional self-harm by exposure to or harmful effects of corrosive substances PD05 Intentional self-harm by exposure to or harmful effects of other or unspecified substances chiefly nonmedicinal as to source PH40 Exposure to or harmful effects of undetermined intent of opioids or related analgesics PH41 Exposure to or harmful effects of undetermined intent of sedative hypnotic drugs or other CNS depressants PH42 Exposure to or harmful effects of undetermined intent of psychostimulants PH43 Exposure to or harmful effects of undetermined intent of cannabinoids or hallucinogens PH44 Exposure to or harmful effects of undetermined intent of analgesics, antipyretics or nonsteroidal anti-inflammatory drugs PH45 Exposure to or harmful effects of undetermined intent of antidepressants PH46 Exposure to or harmful effects of undetermined intent of antipsychotics PH47 Exposure to or harmful effects of undetermined intent of antiepileptics or antiparkinsonism drugs – PH47.0 Harmful effects of or exposure to mixed antiepileptics, not elsewhere classified, undetermined intent – PH47.Z Undetermined intent: Harmful effects of and exposure to noxious substances: Drugs, medicaments or biological substances: Unspecified antiepileptics or antiparkinsonism drugs PH48 Exposure to or harmful effects of undetermined intent of other or unspecified drugs, medicaments or biological substances PH49 Exposure to or harmful effects of undetermined intent of multiple drugs, medicaments or biological substances PH50 Exposure to or harmful effects of undetermined intent of alcohols PH51 Exposure to or harmful effects of undetermined intent of organic solvents PH52 Exposure to or harmful effects of undetermined intent of carbon monoxide PH53 Exposure to or harmful effects of undetermined intent of pesticides PH54 Exposure to or harmful effects of undetermined intent of corrosive substances PH55 Exposure to or harmful effects of undetermined intent of halogen derivatives of aliphatic or aromatic hydrocarbons PH56 Exposure to or harmful effects of undetermined intent of other or unspecified substances chiefly nonmedicinal as to source PL00 Drugs, medicaments or biological substances associated with injury or harm in therapeutic use PL01 Complementary or traditional medicines associated with injury or harm in therapeutic use PL01.0 Complementary or traditional medicines associated with injury or harm in therapeutic use, Herbal Preparations or Formulas PL01.1 Complementary or traditional medicines associated with injury or harm in therapeutic use, Dietary Supplements, Vitamins or Minerals PL01.2 Complementary or traditional medicines associated with injury or harm in therapeutic use, Complementary or Traditional Medicines, not elsewhere classified PL01.Y Other specified complementary or traditional medicines associated with injury or harm in therapeutic use PL01.Z Complementary or traditional medicines associated with injury or harm in therapeutic use, unspecified PL0Z Substances associated with injury or harm in therapeutic use, unspecified Has severity - only one may be selected [select] XS5W Mild XS0T Moderate XS25 Severe Has causing condition - a selection is required - multiple selections are allowed [select] 6C43.0 Episode of harmful use of opioids 6C43.1 Harmful pattern of use of opioids – 6C43.10 Harmful pattern of use of opioids, episodic – 6C43.11 Harmful pattern of use of opioids, continuous – 6C43.1Z Harmful pattern of use of opioids, unspecified 6C43.2 Opioid dependence – 6C43.20 Opioid dependence, current use – 6C43.21 Opioid dependence, early full remission – 6C43.22 Opioid dependence, sustained partial remission – 6C43.23 Opioid dependence, sustained full remission – 6C43.2Z Opioid dependence, unspecified
synonyms Opioid intoxication heroin intoxication bad trip due to opioids Acute intoxication due to fentanyl acute fentanyl toxicity Fentanyl and despropionyl fentanyl intoxication Fentanyl and acetyl fentanyl intoxication Acute intoxication by the combined effects of fentanyl and heroin acute fentanyl and heroin intoxication fentanyl and heroin intoxication Morphine intoxication morphine toxicity Acute methadone intoxication Methadone intoxication Oxycodone intoxication
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