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8A41 Isolated demyelinating syndromes of the central nervous system

International Classification of Diseases for Mortality and Morbidity Statistics, 11th Revision, v2024-01

Clinically isolated syndrome (CIS) is the first clinical inflammatory demyelinating event of the central nervous system, lasting more than 24 hours. CIS is now recognised as the first clinical presentation of a disease that shows characteristics of inflammatory demyelination that could be MS, but has yet to fulfill criteria of dissemination in time.

code elsewhere

• Optic neuritis  (9C40.1)
• Idiopathic inflammatory optic neuropathy  (9C40.1Y)

sections/codes in this section (8A41-8A41)

• Transverse myelitis  (8A41.0)
• Neuromyelitis optica myelin oligodendrocyte glycoprotein antibody-positive  (8A41.1)
• Other specified isolated demyelinating syndromes of the central nervous system  (8A41.Y)
• Isolated demyelinating syndromes of the central nervous system, unspecified  (8A41.Z)

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