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3B62.3 Dense granule disease

International Classification of Diseases for Mortality and Morbidity Statistics, 11th Revision, v2024-01

A condition caused by determinants arising after birth, in the antenatal period. This condition is characterised by defects in the dense granules in platelets leading to abnormalities in coagulation mechanisms. This condition may present with prolonged bleeding, epistaxis, menorrhagia, easy bruising, anaemia, fatigue or shortness of breath. Confirmation is by identification of platelet defects in a blood sample.

code elsewhere

• Hermansky-Pudlak syndrome  (EC23.20)
• Chédiak-Higashi syndrome  (EC23.20)

synonyms

• Dense granule disease
• Isolated delta-storage pool disease
• Isolated dense storage pool disease
• Isolated delta- SPD - [storage pool disease]
• Isolated dense SPD - [storage pool disease]
• Familial platelet syndrome with predisposition to acute myelogenous leukaemia

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