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5C58.10 Porphyria cutanea tarda

International Classification of Diseases for Mortality and Morbidity Statistics, 11th Revision, v2024-01

Porphyria cutanea tarda (PCT) is due to an accumulation of uroporphyrins in plasma from blockage of the normal haem synthetic pathway in the liver at the level of uroporphyrinogen decarboxylase (URO-D). The majority of cases are sporadic and frequently associated with iron overload. PCT manifests as skin fragility and blistering in light-exposed skin, particularly on the dorsa of the hands, together with hypertrichosis.

synonyms

• Porphyria cutanea tarda
• Porphyria, hepatocutaneous type
• Heterozygous uroporphyrinogen decarboxylase deficiency
• UROD - [uroporphyrinogen decarboxylase] deficiency
• PCT - [porphyria cutanea tarda]
• Sporadic porphyria cutanea tarda
• Sporadic PCT - [porphyria cutanea tarda]
• Familial porphyria cutanea tarda
• Familial PCT - [porphyria cutanea tarda]
• Toxic porphyria cutanea tarda
• Porphyria turcica

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