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DA21.3 Disorder of lower oesophageal sphincter function International Classification of Diseases for Mortality and Morbidity Statistics, 11th Revision, v2024-01 Disorder of lower oesophageal sphincter function is a condition characterised by dysphagia, chest pain, heartburn and regurgitation due to incompetence of lower oesophageal sphincter.
postcoordination Add Stem and/or Extension codes to form a cluster code which adds detail to the condition.
Associated with - multiple selections are allowed [select] ME24 Clinical manifestations of the digestive system – ME24.0 Digestive system abscess – ME24.1 Digestive system fistula – ME24.2 Digestive system obstruction – ME24.3 Digestive system perforation – ME24.4 Digestive system stenosis – ME24.5 Digestive system ulcer – ME24.6 Digestive system dilatation – ME24.7 Digestive system incarceration – ME24.8 Digestive system strangulation or gangrene – ME24.9 Gastrointestinal bleeding – ME24.A Other digestive system haemorrhage, not elsewhere classified – ME24.Y Other specified clinical manifestations of the digestive system –– ME24.30 Perforation of small intestine –– ME24.31 Perforation of large intestine –– ME24.35 Perforation of gallbladder or bile ducts –– ME24.3Y Digestive system perforation of other specified site –– ME24.3Z Digestive system perforation of unspecified site –– ME24.90 Acute gastrointestinal bleeding, not elsewhere classified –– ME24.91 Chronic gastrointestinal bleeding, not elsewhere classified –– ME24.9Z Gastrointestinal bleeding, unspecified –– ME24.A0 Obscure gastrointestinal bleeding –– ME24.A1 Haemorrhage of anus and rectum –– ME24.A2 Oesophageal haemorrhage –– ME24.A3 Haematochezia –– ME24.A4 Melaena –– ME24.A5 Haematemesis –– ME24.A6 Positive occult blood in stool Course - only one may be selected [select] XT5R Acute XT8W Chronic Has causing condition - a selection is required - multiple selections are allowed [select] 4A40 Lupus erythematosus – 4A40.0 Systemic lupus erythematosus – 4A40.1 Drug-induced lupus erythematosus – 4A40.Y Other specified lupus erythematosus – 4A40.Z Lupus erythematosus, unspecified –– 4A40.00 Systemic lupus erythematosus with skin involvement –– 4A40.0Y Other specified systemic lupus erythematosus –– 4A40.0Z Systemic lupus erythematosus, unspecified 4A41 Idiopathic inflammatory myopathy – 4A41.0 Dermatomyositis – 4A41.1 Polymyositis – 4A41.2 Inclusion body myopathy – 4A41.Y Other specified idiopathic inflammatory myopathy – 4A41.Z Idiopathic inflammatory myopathy, unspecified –– 4A41.00 Adult dermatomyositis –– 4A41.01 Juvenile dermatomyositis –– 4A41.0Z Dermatomyositis, unspecified –– 4A41.10 Juvenile polymyositis –– 4A41.11 Paraneoplastic polymyositis –– 4A41.1Y Other specified polymyositis –– 4A41.1Z Polymyositis, unspecified –– 4A41.20 Inflammatory inclusion body myositis –– 4A41.21 Noninflammatory inclusion body myopathy –– 4A41.2Z Inclusion body myopathy, unspecified 4A42 Systemic sclerosis – 4A42.0 Paediatric onset systemic sclerosis – 4A42.1 Diffuse systemic sclerosis – 4A42.2 Limited systemic sclerosis – 4A42.Z Systemic sclerosis, unspecified 4A43 Overlap or undifferentiated nonorgan specific systemic autoimmune disease – 4A43.0 IgG4 related disease – 4A43.1 Mikulicz disease – 4A43.2 Sjögren syndrome – 4A43.3 Mixed connective tissue disease – 4A43.4 Diffuse eosinophilic fasciitis – 4A43.Y Other specified overlap non-organ specific systemic autoimmune disease – 4A43.Z Undifferentiated non-organ specific systemic autoimmune disease –– 4A43.20 Primary Sjögren syndrome –– 4A43.21 Secondary Sjögren syndrome –– 4A43.22 Paediatric onset Sjögren syndrome –– 4A43.2Y Other specified sjögren syndrome –– 4A43.2Z Sjögren syndrome, unspecified 4A44 Vasculitis – 4A44.0 Rhizomelic pseudopolyarthritis – 4A44.1 Aortic arch syndrome – 4A44.2 Giant cell arteritis – 4A44.3 Single organ vasculitis – 4A44.4 Polyarteritis nodosa – 4A44.5 Mucocutaneous lymph node syndrome – 4A44.6 Sneddon syndrome – 4A44.7 Primary angiitis of the central nervous system – 4A44.8 Thromboangiitis obliterans – 4A44.9 Immune complex small vessel vasculitis – 4A44.A Antineutrophil cytoplasmic antibody-associated vasculitis – 4A44.B Leukocytoclastic vasculitis – 4A44.Y Other specified vasculitis – 4A44.Z Vasculitis, unspecified –– 4A44.90 Cryoglobulinaemic vasculitis –– 4A44.91 Hypocomplementaemic urticarial vasculitis –– 4A44.92 IgA vasculitis –– 4A44.9Y Other specified immune complex small vessel vasculitis –– 4A44.9Z Immune complex small vessel vasculitis, unspecified –– 4A44.A0 Microscopic polyangiitis –– 4A44.A1 Granulomatosis with polyangiitis –– 4A44.A2 Eosinophilic granulomatosis with polyangiitis –– 4A44.AY Other specified antineutrophil cytoplasmic antibody-associated vasculitis –– 4A44.AZ Antineutrophil cytoplasmic antibody-associated vasculitis, unspecified –– 4A44.B0 Cutaneous leukocytoclastic vasculitis –– 4A44.BY Other specified leukocytoclastic vasculitis –– 4A44.BZ Leukocytoclastic vasculitis, unspecified 4A45 Antiphospholipid syndrome – 4A45.0 Primary antiphospholipid syndrome – 4A45.1 Secondary antiphospholipid syndrome – 4A45.2 Antiphospholipid syndrome in pregnancy – 4A45.3 Lupus anticoagulant-hypoprothrombinaemia syndrome – 4A45.Z Antiphospholipid syndrome, unspecified 4A4Y Other specified nonorgan specific systemic autoimmune disorders 4A4Z Nonorgan specific systemic autoimmune disorders, unspecified – 5A00 Hypothyroidism –– 5A00.0 Congenital hypothyroidism –– 5A00.1 Iodine-deficiency-related thyroid disorders or allied conditions –– 5A00.2 Acquired hypothyroidism –– 5A00.Z Hypothyroidism, unspecified ––– 5A00.00 Permanent congenital hypothyroidism with diffuse goitre ––– 5A00.01 Permanent congenital hypothyroidism without goitre ––– 5A00.02 Pendred syndrome ––– 5A00.03 Transient congenital hypothyroidism ––– 5A00.04 Congenital hypothyroidism due to iodine deficiency ––– 5A00.0Y Other specified congenital hypothyroidism ––– 5A00.0Z Congenital hypothyroidism, unspecified ––– 5A00.10 Iodine-deficiency-related diffuse goitre ––– 5A00.11 Iodine-deficiency-related multinodular goitre ––– 5A00.1Z Iodine-deficiency-related thyroid disorders or allied conditions, unspecified ––– 5A00.20 Hypothyroidism due to medicaments or other exogenous substances ––– 5A00.21 Myxoedema coma ––– 5A00.22 Subclinical iodine-deficiency hypothyroidism ––– 5A00.2Y Other specified acquired hypothyroidism ––– 5A00.2Z Acquired hypothyroidism, unspecified – 5A01 Nontoxic goitre –– 5A01.0 Nontoxic diffuse goitre –– 5A01.1 Nontoxic single thyroid nodule –– 5A01.2 Nontoxic multinodular goitre –– 5A01.Z Nontoxic goitre, unspecified – 5A02 Thyrotoxicosis –– 5A02.0 Thyrotoxicosis with diffuse goitre –– 5A02.1 Thyrotoxicosis with toxic single thyroid nodule –– 5A02.2 Thyrotoxicosis with toxic multinodular goitre –– 5A02.3 Thyrotoxicosis from ectopic thyroid tissue –– 5A02.4 Thyrotoxicosis factitia –– 5A02.5 Thyroid crisis –– 5A02.6 Secondary hyperthyroidism –– 5A02.Y Other specified thyrotoxicosis –– 5A02.Z Thyrotoxicosis, unspecified – 5A03 Thyroiditis –– 5A03.0 Acute thyroiditis –– 5A03.1 Subacute thyroiditis –– 5A03.2 Autoimmune thyroiditis –– 5A03.Y Other specified thyroiditis –– 5A03.Z Thyroiditis, unspecified ––– 5A03.20 Hashimoto thyroiditis ––– 5A03.21 Painless thyroiditis ––– 5A03.2Y Other specified autoimmune thyroiditis ––– 5A03.2Z Autoimmune thyroiditis, unspecified – 5A04 Hypersecretion of calcitonin – 5A05 Generalised resistance to thyroid hormone – 5A06 Sick-euthyroid syndrome – 5A0Y Other specified disorders of the thyroid gland or thyroid hormones system – 5A0Z Disorders of the thyroid gland or thyroid hormones system, unspecified – 5A10 Type 1 diabetes mellitus – 5A11 Type 2 diabetes mellitus – 5A12 Malnutrition-related diabetes mellitus – 5A13 Diabetes mellitus, other specified type –– 5A13.0 Diabetes mellitus due to genetic defects of beta cell function –– 5A13.1 Diabetes mellitus due to genetic defects in insulin action –– 5A13.2 Diabetes mellitus due to diseases of the exocrine pancreas –– 5A13.3 Diabetes mellitus due to endocrinopathies –– 5A13.4 Diabetes mellitus due to drug or chemical –– 5A13.5 Diabetes mellitus due to uncommon forms of immune-mediated diabetes –– 5A13.6 Diabetes mellitus due to other genetic syndromes –– 5A13.7 Diabetes mellitus due to clinically defined subtypes or syndromes –– 5A13.Y Diabetes mellitus due to other specified cause – 5A14 Diabetes mellitus, type unspecified –– 5A20 Diabetic hyperosmolar hyperglycaemic state ––– 5A20.0 Hyperosmolar hyperglycaemic state without coma ––– 5A20.1 Hyperosmolar hyperglycaemic state with coma ––– 5A20.Z Diabetic hyperosmolar hyperglycaemic state, unspecified –– 5A21 Hypoglycaemia in the context of diabetes mellitus ––– 5A21.0 Hypoglycaemia in the context of diabetes mellitus without coma ––– 5A21.1 Hypoglycaemia in the context of diabetes mellitus with coma ––– 5A21.Z Hypoglycaemia in the context of diabetes, unspecified –– 5A22 Diabetic acidosis ––– 5A22.0 Diabetic ketoacidosis without coma ––– 5A22.1 Diabetic lactic acidosis ––– 5A22.2 Diabetic metabolic acidosis ––– 5A22.3 Diabetic ketoacidosis with coma ––– 5A22.Y Other specified diabetic acidosis ––– 5A22.Z Diabetic acidosis, unspecified –– 5A23 Diabetic coma –– 5A24 Uncontrolled or unstable diabetes mellitus –– 5A2Y Other specified acute complications of diabetes mellitus – 5A40 Intermediate hyperglycaemia –– 5A40.0 Impaired fasting glucose –– 5A40.1 Impaired glucose tolerance –– 5A40.Y Other specified intermediate hyperglycaemia –– 5A40.Z Intermediate hyperglycaemia, unspecified – 5A41 Hypoglycaemia without associated diabetes – 5A42 Increased secretion of glucagon – 5A43 Abnormal secretion of gastrin –– 5A43.0 Drug-induced hypergastrinaemia –– 5A43.1 Zollinger-Ellison syndrome –– 5A43.Y Other specified abnormal secretion of gastrin –– 5A43.Z Abnormal secretion of gastrin, unspecified – 5A44 Insulin-resistance syndromes – 5A45 Persistent hyperinsulinaemic hypoglycaemia of infancy – 5A4Y Other specified disorders of glucose regulation or pancreatic internal secretion – 5A4Z Disorders of glucose regulation or pancreatic internal secretion, unspecified – 5A50 Hypoparathyroidism –– 5A50.0 Hypoparathyroidism due to impaired parathyroid hormone secretion –– 5A50.1 Pseudohypoparathyroidism –– 5A50.Y Other specified hypoparathyroidism –– 5A50.Z Hypoparathyroidism, unspecified ––– 5A50.00 Idiopathic hypoparathyroidism ––– 5A50.01 Secondary hypoparathyroidism ––– 5A50.02 Hypoparathyroidism due to destruction of the parathyroid glands ––– 5A50.03 Autoimmune hypoparathyroidism ––– 5A50.0Y Other specified hypoparathyroidism due to impaired parathyroid hormone secretion ––– 5A50.0Z Hypoparathyroidism due to impaired parathyroid hormone secretion, unspecified – 5A51 Hyperparathyroidism –– 5A51.0 Primary hyperparathyroidism –– 5A51.1 Secondary hyperparathyroidism –– 5A51.2 Familial hypocalciuric hypercalcaemia –– 5A51.Y Other specified hyperparathyroidism –– 5A51.Z Hyperparathyroidism, unspecified – 5A5Y Other specified disorders of the parathyroids or parathyroid hormone system – 5A5Z Disorders of the parathyroids or parathyroid hormone system, unspecified – 5A60 Hyperfunction of pituitary gland –– 5A60.0 Acromegaly or pituitary gigantism –– 5A60.1 Hyperprolactinaemia –– 5A60.2 Syndrome of inappropriate secretion of antidiuretic hormone –– 5A60.3 Central precocious puberty –– 5A60.Y Other specified hyperfunction of pituitary gland –– 5A60.Z Hyperfunction of pituitary gland, unspecified ––– 5A60.20 Nephrogenic syndrome of inappropriate antidiuresis ––– 5A60.2Y Other specified syndrome of inappropriate secretion of antidiuretic hormone ––– 5A60.2Z Syndrome of inappropriate secretion of antidiuretic hormone, unspecified – 5A61 Hypofunction or certain other specified disorders of pituitary gland –– 5A61.0 Hypopituitarism –– 5A61.1 Adrenocorticotropic hormone deficiency –– 5A61.2 Gonadotropin deficiency –– 5A61.3 Growth hormone deficiency –– 5A61.4 Thyroid stimulating hormone deficiency –– 5A61.5 Central diabetes insipidus –– 5A61.6 Oxytocin deficiency –– 5A61.Y Other specified hypofunction or disorders of pituitary gland ––– 5A61.40 Acquired central hypothyroidism ––– 5A61.41 Congenital central hypothyroidism ––– 5A61.4Y Other specified thyroid stimulating hormone deficiency ––– 5A61.4Z Thyroid stimulating hormone deficiency, unspecified – 5A6Z Disorders of the pituitary hormone system, unspecified – 5A70 Cushing syndrome –– 5A70.0 Pituitary-dependent Cushing disease –– 5A70.1 Ectopic ACTH syndrome –– 5A70.2 Pseudo-Cushing syndrome –– 5A70.3 Nelson syndrome –– 5A70.Y Other specified Cushing syndrome –– 5A70.Z Cushing syndrome, unspecified – 5A71 Adrenogenital disorders –– 5A71.0 46,XX disorders of sex development induced by androgens of fetal origin –– 5A71.1 46,XX disorders of sex development induced by androgens of maternal origin –– 5A71.Y Other specified adrenogenital disorders –– 5A71.Z Adrenogenital disorders, unspecified ––– 5A71.00 Glucocorticoid resistance ––– 5A71.01 Congenital adrenal hyperplasia ––– 5A71.0Y Other specified 46,XX disorders of sex development induced by androgens of fetal origin ––– 5A71.0Z 46,XX disorders of sex development induced by androgens of fetal origin, unspecified – 5A72 Hyperaldosteronism –– 5A72.0 Primary hyperaldosteronism –– 5A72.1 Secondary hyperaldosteronism –– 5A72.Z Hyperaldosteronism, unspecified – 5A73 Hypoaldosteronism – 5A74 Adrenocortical insufficiency –– 5A74.0 Acquired adrenocortical insufficiency –– 5A74.1 Adrenal crisis –– 5A74.Y Other specified adrenocortical insufficiency –– 5A74.Z Adrenocortical insufficiency, unspecified – 5A75 Adrenomedullary hyperfunction – 5A76 Certain specified disorders of adrenal gland –– 5A76.0 Premature adrenarche –– 5A76.Y Other specified disorders of adrenal gland – 5A7Z Disorders of the adrenal glands or adrenal hormone system, unspecified – 5A80 Ovarian dysfunction –– 5A80.0 Clinical hyperandrogenism –– 5A80.1 Polycystic ovary syndrome –– 5A80.2 Polycystic ovary –– 5A80.3 Anovulation –– 5A80.4 Oligo-ovulation –– 5A80.5 Diminished ovarian reserve –– 5A80.Y Other specified ovarian dysfunction –– 5A80.Z Ovarian dysfunction, unspecified – 5A81 Testicular dysfunction or testosterone-related disorders –– 5A81.0 Testicular hyperfunction –– 5A81.1 Testicular hypofunction –– 5A81.Y Other specified testicular dysfunction or testosterone-related disorders –– 5A81.Z Testicular dysfunction or testosterone-related disorders, unspecified – 5A8Z Disorders of the gonadal hormone system, unspecified – 5A90 Disorder of puberty due to oestrogen resistance – 5A91 Delayed puberty – 5A92 Peripheral precocious puberty – 5A9Y Other disorders of puberty – 5A9Z Disorders of puberty, unspecified – 5B00 Autoimmune polyendocrinopathy – 5B01 Polyglandular hyperfunction – 5B0Y Other specified polyglandular dysfunction – 5B0Z Polyglandular dysfunction, unspecified – 5B10 Carcinoid syndrome – 5B11 Short stature, not elsewhere classified – 5B12 Constitutional tall stature – 5B1Y Other specified endocrine disorders, not elsewhere classified 5B3Y Other specified endocrine diseases 5B3Z Endocrine diseases, unspecified
synonyms Disorder of lower oesophageal sphincter function Hypertensive lower oesophageal sphincter Hypotensive lower oesophageal sphincter Incomplete lower oesophageal sphincter relaxation lack of reflex relaxation of lower oesophageal sphincter
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