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8C70.40 Dominant limb-girdle muscular dystrophy International Classification of Diseases for Mortality and Morbidity Statistics, 11th Revision, v2024-01 The Limb Girdle Muscular Dystrophies (LGMD) are a group of genetic disorders characterised predominantly by progressive wasting and weakness of proximal limb girdle muscles, including pelvic, shoulder, upper arm and thigh muscles. The onset symptoms usually vary from early childhood to late adulthood, and the progression rate and distribution of weakness and wasting also varies considerably among individuals and genetic subtypes. There are currently 8 autosomal dominant LGMDs (LGMD1), linked to specific gene mutations. Dominant LGMDs are often allelic with other clinical disorders, including the myofibrillar myopathies or dilated cardiomyopathy.
exclusions postcoordination Add Stem and/or Extension codes to form a cluster code which adds detail to the condition.
Laterality - only one may be selected [select] XK9J Bilateral XK8G Left XK9K Right XK70 Unilateral, unspecified Specific anatomy - multiple selections are allowed [select] XA2JQ8 Muscles of the head and neck – XA2SJ6 Alaeque nasi muscle – XA2QF2 Anterior auricularis muscle – XA3SS4 Aryepiglotticus muscle – XA8GG0 Buccinator muscle – XA0UH6 Constrictor of pharynx - inferior muscle – XA3S80 Constrictor of pharynx - middle muscle – XA9568 Constrictor of pharynx - superior muscle – XA01U4 Corrugator supercilii muscle – XA7W64 Cricothyroid muscle – XA04G0 Depressor anguli oris muscle – XA60C8 Depressor labii inferioris muscle – XA2967 Digastric muscle – XA09D1 Frontalis muscle – XA50R5 Genioglossus muscle – XA5YU7 Geniohyoid muscle – XA5DX5 Hyoglossus muscle – XA3PY5 Hyoid muscle – XA4N79 Inferior oblique muscle – XA1X67 Inferior rectus muscle – XA31C3 Intrinsic muscles of tongue – XA5WQ9 Lateral cricoarytenoid muscle – XA8ZB7 Lateral pterygoid muscle – XA3282 Lateral rectus muscle – XA75X0 Levator anguli oris muscle – XA1490 Levator labii superioris muscle – XA2R46 Levator palpebrae superioris muscle – XA5LP4 Levator veli palatini muscle – XA6YE6 Longus capitis muscle – XA8EM8 Longus colli muscle – XA2VD8 Masseter muscle – XA2DX4 Medial pterygoid muscle – XA95N1 Medial rectus muscle – XA0U25 Mentalis muscle – XA8AR7 Musculus uvulae muscle – XA83A9 Mylohyoid muscle – XA0Y41 Nasalis muscle – XA59J0 Oblique arytenoid muscle – XA8L72 Oblique auricularis muscle – XA6LS5 Obliquus capitis inferior muscle – XA0X13 Obliquus capitis superior muscle – XA4RN7 Omohyoid muscle – XA0ZM1 Orbicularis oculi muscle – XA55R2 Orbicularis oris muscle – XA2U72 Palatoglossus muscle – XA1PG4 Palatopharyngeus muscle – XA17T6 Platysma muscle – XA8C48 Posterior auricularis muscle – XA9RS8 Posterior cricoarytenoid muscle – XA6648 Procerus muscle – XA16A4 Rectus capitis anterior muscle – XA0JK2 Rectus capitis lateralis muscle – XA20Q8 Rectus capitis posterior major muscle – XA80F2 Rectus capitis posterior minor muscle – XA49A7 Risorius muscle – XA81P5 Salpingopharyngeus muscle – XA0JF1 Scalenus anterior muscle – XA6S71 Scalenus medius muscle – XA3TF5 Scalenus minimus muscle – XA35K5 Scalenus posterior muscle – XA58T9 Splenius capitis muscle – XA6095 Splenius cervicis muscle – XA8D61 Stapedius muscle – XA2H61 Sternocleidomastoid muscle – XA5QR5 Sternohyoid muscle – XA9H91 Sternothyroid muscle – XA5L15 Styloglossus muscle – XA1TY3 Stylohyoid muscle – XA9AM5 Stylopharyngeus muscle – XA8SW4 Superior auricularis muscle – XA2X27 Superior oblique muscle – XA51R1 Superior rectus muscle – XA01H9 Temporalis muscle – XA1CQ1 Temporoparietalis muscle – XA42R7 Tensor tympani muscle – XA7LF2 Tensor veli palatini muscle – XA8352 Thyroarytenoid muscle – XA2ZL4 Thyroepiglotticus muscle – XA87S0 Thyrohyoid muscle – XA3856 Transverse arytenoid muscle – XA9AU8 Transverse auricularis muscle – XA0M12 Vocalis muscle – XA37U4 Zygomaticus major muscle – XA2AP2 Zygomaticus minor muscle XA19W0 Muscle of the thorax – XA2JL0 Diaphragm – XA6RW0 External intercostal muscle – XA3P12 Innermost intercostal muscle – XA1256 Internal intercostal muscle – XA7NL0 Levator costarum muscle – XA1QH6 Pectoralis major muscle – XA0SB2 Pectoralis minor muscle – XA7QL8 Serratus anterior muscle – XA44Y8 Subcostalis muscle – XA3G64 Transversus thoracis muscle XA8PG5 Muscle of the abdomen – XA3TW8 External oblique abdominis muscle – XA9B36 Internal oblique abdominis muscle – XA43E9 Psoas major muscle – XA7DA1 Psoas minor muscle – XA6AY9 Pyramidalis muscle – XA1GP3 Quadratus lumborum muscle – XA1N65 Rectus abdominis muscle – XA9FR3 Transversus abdominis muscle XA8Z76 Muscle of the back – XA19S9 Iliocostalis muscle – XA8YU1 Interspinales muscle – XA02Z7 Intertransversarii muscle – XA9AG9 Latissimus dorsi muscle – XA00C1 Levator scapulae muscle – XA6MB7 Longissimus muscle – XA8512 Multifidus muscle – XA25S1 Rhomboid major muscle – XA5GH5 Rhomboid minor muscle – XA76Q0 Rotatores muscle – XA60Q0 Semispinalis muscle – XA4A47 Serratus posterior inferior muscle – XA15B6 Serratus posterior superior muscle – XA0U57 Spinalis muscle – XA7RM2 Teres major muscle – XA86Q8 Trapezius muscle – XA3YC6 Iliococcygeus muscle – XA73H8 Ischiocavernosus muscle – XA9T66 Levator ani-coccygeus muscle – XA3HP4 Pubococcygeus muscle – XA7MM8 Puborectalis muscle – XA4RK4 Pubovaginalis muscle – XA3ML6 Sphincter ani muscle – XA8FT0 Sphincter urethrae muscle – XA56U7 Superficial transverse perinei muscle XA2J71 Muscles of the pelvis and perineum – XA2E07 Bulbospongiosus muscle – XA5FZ1 Cremaster muscle – XA8HG2 Dartos muscle – XA2LG6 Deep transverse perinei muscle XA4Z20 Muscles of the upper extremity – XA90T3 Abductor digiti minimi muscle (hand) – XA0Z05 Abductor pollicis brevis muscle – XA7PS1 Abductor pollicis longus muscle – XA54Z7 Adductor pollicis muscle – XA2583 Anconeus muscle – XA0GV5 Articularis cubiti muscle – XA1KL5 Biceps brachii muscle –– XA0481 Long head of the biceps brachii muscle –– XA3J17 Short head of the biceps brachii muscle – XA6CR7 Brachialis muscle – XA2ZN1 Brachioradialis muscle – XA0TQ5 Coracobrachialis muscle – XA3VN0 Deltoid muscle – XA4U40 Extensor carpi radialis brevis – XA8824 Extensor carpi radialis longus muscle – XA9304 Extensor carpi ulnaris muscle – XA0T60 Extensor digiti minimi muscle (hand) – XA7QU8 Extensor digitorum muscle (hand) – XA1AV6 Extensor indicis muscle – XA4V20 Extensor pollicis brevis muscle – XA0CS4 Extensor pollicis longus muscle – XA0S07 Flexor carpi radialis muscle – XA4HV9 Flexor carpi ulnaris muscle – XA3UK3 Flexor digiti minimi brevis muscle (hand) – XA4Z43 Flexor digitorum profundus muscle – XA1NW3 Flexor digitorum superficialis muscle – XA5QD0 Flexor pollicis brevis muscle – XA3GQ7 Flexor pollicis longus muscle – XA6463 Interossei of the hand muscle –– XA2QW3 Dorsal interossei of the hand muscle –– XA5055 Palmar interossei of the hand muscle – XA9B77 Lumbricals of hand muscle – XA4RW9 Opponens digiti minimi muscle (hand) – XA0Q73 Opponens pollicis muscle – XA9KL5 Palmaris brevis muscle – XA6P76 Palmaris longus muscle – XA91W0 Pronator quadratus muscle – XA58Z6 Pronator teres muscle – XA3DL4 Rotator cuff muscle –– XA7E49 Infraspinatus muscle –– XA1QF1 Subscapularis muscle –– XA74P3 Supraspinatus muscle –– XA3CP1 Teres minor muscle – XA90Z6 Supinator muscle – XA2EB2 Triceps brachii muscle XA47J0 Muscles of the lower extremity – XA0W07 Abductor digiti minimi muscle (foot) – XA7119 Abductor hallucis muscle – XA8GU7 Adductor brevis muscle – XA0FW7 Adductor hallucis muscle – XA01U3 Adductor longus muscle – XA8HR3 Adductor magnus muscle – XA0DE1 Articularis genu muscle – XA3CB9 Biceps femoris muscle – XA7FZ1 Extensor digitorum brevis muscle (foot) – XA24U7 Extensor digitorum longus muscle (foot) – XA3T27 Extensor hallucis brevis muscle – XA7R67 Extensor hallucis longus muscle – XA20W3 Flexor digiti minimi brevis muscle (foot) – XA97C3 Flexor digitorum brevis muscle – XA23Q3 Flexor digitorum longus muscle (foot) – XA3MB7 Flexor hallucis brevis muscle – XA7E33 Flexor hallucis longus muscle – XA1PK6 Gastrocnemius muscle – XA7PN8 Gemellus inferior muscle – XA0472 Gemellus superior muscle – XA1HH2 Gracilis muscle – XA0200 Iliacus muscle – XA15P6 Interossei - dorsal of foot muscle – XA8TS8 Interossei - plantar of foot muscle – XA7PN0 Lumbricals of foot muscle – XA7Y24 Obturator externus muscle – XA11E8 Obturator internus muscle – XA9E00 Pectineus muscle – XA26M7 Peroneus brevis muscle – XA3P60 Peroneus longus muscle – XA9D52 Peroneus tertius muscle – XA7XS8 Piriformis muscle – XA7W96 Plantaris muscle – XA8CL8 Popliteus muscle – XA41G3 Quadratus plantae muscle – XA1BT5 Quadriceps femoris muscle – XA5447 Rectus femoris muscle – XA5CE3 Sartorius muscle – XA5AM5 Semimembranosus muscle – XA2EK1 Semitendinosus muscle – XA5B83 Soleus muscle – XA02U9 Tibialis anterior muscle – XA3VR3 Tibialis posterior muscle – XA33F6 Vastus intermedius muscle – XA00Z6 Vastus lateralis muscle – XA9RD2 Vastus medialis muscle – XA48F2 Gluteus maximus muscle – XA5VJ8 Gluteus medius muscle – XA7BY4 Gluteus minimus muscle – XA11U3 Tensor fasciae lata muscle
synonyms Dominant limb-girdle muscular dystrophy LGMD1 - [limb-girdle muscular dystrophy] 1 Limb-girdle muscular dystrophy 1A, myotilin myopathy LGMD 1A - [Limb-girdle muscular dystrophy 1A, myotilin myopathy] Limb-girdle muscular dystrophy 1B, lamin myopathy LGMD 1B - [Limb-girdle muscular dystrophy 1B, lamin myopathy] Limb-girdle muscular dystrophy 1C, caveolin myopathy LGMD 1C - [Limb-girdle muscular dystrophy 1C, caveolin myopathy] Limb-girdle muscular dystrophy 1D, gene mapped to 6q23 Limb-girdle muscular dystrophy 1E, gene mapped to 7q Limb-girdle muscular dystrophy 1F, gene mapped to 7q32.1-32.2 Limb-girdle muscular dystrophy 1G, gene mapped to 4q21 Limb-girdle muscular dystrophy 1H, gene mapped to 3p25.1p23 LGMD1H - [Limb-girdle muscular dystrophy] 1H
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