2B6B Malignant neoplasms of nasopharynx International Classification of Diseases for Mortality and Morbidity Statistics, 11th Revision, v2024-01 A wide variety of tumours can arise in the nasopharynx, but it is nasopharyngeal carcinoma that has fascinated generations of oncologists, pathologists, scientists and epidemiologists. It shows marked geographic differences, with highest incidence rates in Southern China. In some endemic areas, the incidence has declined by about 30% over the past two decades, suggesting that environmental or lifestyle factors may play a major role and that the disease is, to some extent, preventable. Nasopharyngeal carcinoma shows a very strong association with Epstein-Barr virus (EBV) infection, irrespective of the ethnic origin of the patients. This association has pioneered a new paradigm of utilizing viral serological tests for the diagnosis of cancer and for screening in high-risk populations. Nasopharyngeal carcinoma is generally responsive to radiation therapy, and the clinical outcome has greatly improved over the years, due to refinements in staging and to improved therapy protocols. The unusual and often deceptive histological features of nasopharyngeal carcinoma have generated controversies over the nature of the tumour and still pose a challenge to surgical pathologists. There have possibly been more names invented for the various histological subtypes of nasopharyngeal carcinoma than any other tumour type.
exclusions sections/codes in this section (2B6B-2B6B) postcoordination Add Stem and/or Extension codes to form a cluster code which adds detail to the condition.
Specific anatomy - multiple selections are allowed [select] XA9AZ1 Nasopharynx – XA0659 Superior wall of nasopharynx – XA21P9 Anterior wall of nasopharynx – XA4BR4 Posterior wall of nasopharynx –– XA5AS8 Adenoid – XA7PX5 Lateral wall of nasopharynx –– XA7W35 Pharyngeal recess ––– XA9P89 Retropharyngeal recess ––– XA6QY3 Parapharyngeal recess Histopathology - only one may be selected [select] XH2WJ3 Malignant histiocytosis XH7PV7 Histiocytic medullary reticulosis XH4XT4 Acute progressive histiocytosis X XH8VV4 Histiocytosis X, NOS XH86U0 Hand-Schuller-Christian disease XH60Q1 Letterer-Siwe disease XH0YE1 Nonlipid reticuloendotheliosis XH40U7 Langerhans cell histiocytosis, disseminated XH4JD4 Histiocytic sarcoma XH46Q0 True histiocytic lymphoma XH8J76 Langerhans cell sarcoma XH7UM7 Interdigitating dendritic cell sarcoma XH8Q19 Dendritic cell sarcoma, NOS XH3ZM0 Indeterminate dendritic cell tumour XH1JT6 Follicular dendritic cell sarcoma XH6ZR5 Follicular dendritic cell tumour XH0124 Fibroblastic reticular cell tumour XH75E6 Eosinophilic granuloma XH3PG9 Acinar cell carcinoma XH99S4 Acinar cell cystadenocarcinoma XH9B93 Mixed acinar-ductal carcinoma XH0F68 Acinar adenocarcinoma of the lung XH2ZQ0 Adenocarcinoma with mixed subtypes XH0349 Adenocarcinoma, intestinal type XH8B45 Solid carcinoma, NOS XH8DS0 Neuroendocrine tumour, NOS XH8LX8 Neuroendocrine carcinoma, low grade XH55D7 Neuroendocrine carcinoma, well-differentiated XH9LV8 Neuroendocrine tumor, grade 1 XH7NM1 Enterochromaffin cell carcinoid XH0U20 Neuroendocrine carcinoma, NOS XH7F73 Neuroendocrine carcinoma, moderately differentiated XH24W2 Lepidic adenocarcinoma XH3QM0 Minimally invasive adenocarcinoma, Non-mucinous XH4302 Adenoid cystic carcinoma XH2098 Minimally invasive adenocarcinoma, Mucinous XH6LV9 Papillary adenocarcinoma, NOS XH95U1 Villoglandular carcinoma XH6QG3 Micropapillary carcinoma, NOS XH4MW7 Micropapillary adenocarcinoma XH7KL6 Pituitary carcinoma, NOS XH6L02 Clear cell adenocarcinoma, NOS XH5085 Hereditary leiomyomatosis and renal cell carcinoma (HLRCC) syndrome-associated renal cell carcinoma XH1442 MiT Family translocation carcinomas XH8EN1 Succinate dehydrogenase deficient renal cell carcinoma XH07X3 Alveolar adenocarcinoma XH05V6 Renal cell carcinoma, NOS XH3Z08 Renal cell carcinoma, unclassified XH0RU3 Acquired cystic disease associated renal cell carcinoma XH7K79 Tubulocystic renal cell carcinoma XH1VB1 Hybrid oncocytic chromophobe tumour XH3Z50 Follicular carcinoma, NOS XH9508 Endometrioid adenocarcinoma, ciliated cell variant XH0718 Endometrioid adenocarcinoma, secretory variant XH4KH2 Adrenal cortical carcinoma XH0SD2 Endometrioid adenocarcinoma, NOS XH51K1 Neuroendocrine tumour, grade 2 XH09B7 Endometrioid cystadenocarcinoma XH6KR7 Endometrioid adenofibroma, malignant XH0GS9 Adenocarcinoma, endocervical type XH8SF8 Islet cell adenomatosis XH43E4 Perihilar cholangiocarcinoma XH4BY1 Islet cell adenoma XH3CU4 Villoglandular variant of endometrioid adenocarcinoma XH5QV8 Pituitary blastoma XH0Y80 Follicular carcinoma, encapsulated, angioinvasive XH46F1 Clear cell renal cell carcinoma, NOS XH9SA7 Basal cell adenocarcinoma XH85C2 Endolymphatic sac tumor XH4PB1 Acinar adenocarcinoma of prostate XH8E54 Mixed neuroendocrine non-neuroendocrine neoplasm (MiNEN) XH5QW8 Neuroendocrine tumour, grade 3 XH1NL5 Nesidioblastoma XH5XB7 Islet cell carcinoma XH2ST7 Islet cell tumor, NOS XH4SH8 Insulinoma, NOS XH93H8 Gastrinoma XH7JQ0 Parathyroid carcinoma XH9LV7 Basophil carcinoma XH7152 Glucagon-like peptide-producing tumour XH7LW9 L-cell tumour XH9ZS8 Pancreatic peptide and pancreatic peptide-like peptide within terminal tyrosine amide producing tumour XH4NQ8 Glucagonoma XH2PF0 Enteroglucagonoma XH72E5 Vipoma XH5VH0 Somatostatinoma XH41P2 Endocrine tumour, functioning, NOS XH7AG8 ACTH-producing tumour XH60V1 Medullary thyroid carcinoma XH3BU6 Bile duct cystadenocarcinoma XH2MW1 Medullary carcinoma with amyloid stroma XH8VU6 Poorly differentiated thyroid carcinoma XH4NH4 Pituitary neuroendocrine tumour XH2ZA2 Bronchial adenoma, carcinoid XH5TR7 Adenocarcinoma of lung, mixed mucinous and non-mucinous XH7GY6 Adenocarcinoma of lung, mucinous XH2035 Bronchiolo-alveolar carcinoma, non-mucinous XH6LF9 Carcinoma simplex XH0XL5 Carcinoma, diffuse type XH7M15 Cholangiocarcinoma XH7SS7 Chromophobe carcinoma XH2Q13 Clear cell adenocarcinofibroma XH6YS0 Clear cell adenocarcinoma, mesonephroid XH4SQ4 Collecting duct carcinoma XH7QJ6 Combined hepatocellular carcinoma and cholangiocarcinoma XH4KK0 Cyst-associated renal cell carcinoma XH0LH8 Enterochromaffin-like cell tumour XH5P16 Fetal adenocarcinoma XH7TE3 Follicular adenocarcinoma, moderately differentiated XH0VD1 Follicular adenocarcinoma, trabecular XH8FK7 Follicular adenocarcinoma, well differentiated XH3DN7 Follicular carcinoma, minimally invasive XH90N9 Follicular carcinoma, oxyphilic cell XH3XT5 Glycogen-rich carcinoma XH4262 Goblet cell carcinoid XH2EH4 Granular cell carcinoma XH4T58 Hepatocellular carcinoma, clear cell type XH9Q35 Hepatocellular carcinoma, fibrolamellar XH0G90 Hepatocellular carcinoma, pleomorphic type XH5761 Hepatocellular carcinoma, scirrhous XH3T17 Hepatocellular carcinoma, spindle cell variant XH6YH5 Hurthle cell adenocarcinoma XH8MQ3 Hurthle cell carcinoma XH8WM4 Linitis plastica XH6TK0 Lipid-rich carcinoma XH81N8 Merkel cell carcinoma XH7019 Mixed acidophil-basophil carcinoma XH8EZ3 Mixed acinar-endocrine carcinoma XH74Y9 Mixed acinar-endocrine-ductal carcinoma XH6H10 Mixed adenoneuroendocrine carcinoma XH2AM6 Mixed cell adenocarcinoma XH7CY5 Mixed ductal-endocrine carcinoma XH6UP4 Mixed endocrine and exocrine adenocarcinoma XH7DG7 Mixed medullary-follicular carcinoma XH3340 Mixed medullary-papillary carcinoma XH9LZ7 Mixed pancreatic endocrine and exocrine tumour, malignant XH1108 Nonencapsulated sclerosing carcinoma XH09D6 Oxyphilic adenocarcinoma XH3614 Islet cell adenocarcinoma XH3709 Pancreatic neuroendocrine tumor, nonfunctioning XH6XY9 Pancreatobiliary-type carcinoma XH1ND9 Papillary carcinoma of thyroid XH85E5 Papillary carcinoma, columnar cell XH0426 Papillary carcinoma, diffuse sclerosing XH0Q59 Papillary carcinoma, encapsulated, of thyroid XH29M4 Papillary carcinoma, follicular variant XH5YT2 Papillary carcinoma, oncocytic variant XH2AW7 Papillary microcarcinoma XH1D07 Papillary renal cell carcinoma XH4Q20 Papillotubular adenocarcinoma XH1JZ0 Parietal cell carcinoma XH6153 Renal cell carcinoma, chromophobe type XH9DH7 Renal cell carcinoma, sarcomatoid XH4FS4 Scirrhous adenocarcinoma XH34G3 Solid carcinoma with mucin formation XH0JE3 Superficial spreading adenocarcinoma XH7EX3 Trabecular adenocarcinoma XH4TA4 Tubular adenocarcinoma XH1Z69 Typical carcinoid XH22Z8 Carcinoma of Skene, Cowper and Littre Glands XH0X20 Villous adenocarcinoma XH0A57 Water-clear cell adenocarcinoma XH8UE4 Adenocarcinoma, metastatic, NOS XH4ZC3 Basal cell carcinoma of the prostate XH4W48 Hepatocellular carcinoma, NOS XH81Q9 Bronchial adenoma, cylindroid XH92Y9 Thymic carcinoma with adenoid cystic carcinoma-like features XH1YZ3 Cribriform carcinoma, NOS XH4YG1 Cribriform comedo-type carcinoma XH74B2 Serrated adenocarcinoma XH2QZ6 Acidophil carcinoma XH5LA4 Adenocarcinoid tumour XH74S1 Adenocarcinoma, NOS XH7QZ0 Adenocarcinoma in adenomatous polyp XH2ZH8 Adenocarcinoma in adenomatous polyposis coli XH9YR3 Adenocarcinoma in multiple adenomatous polyps XH7QB1 Adenocarcinoma in tubulovillous adenoma XH6DA5 Adenocarcinoma in villous adenoma XH5RE1 Adenocarcinoma of anal glands XH9L77 Apocrine adenocarcinoma XH6FB5 Digital papillary adenocarcinoma XH7VK4 Porocarcinoma, NOS XH58E1 Malignant eccrine spiradenoma XH7NK9 Hidradenocarcinoma XH17P2 Microcystic adnexal carcinoma XH89V4 Adnexal adenocarcinoma, NOS XH5LY3 Sweat gland adenocarcinoma XH4VR2 Sebaceous carcinoma XH8NE4 Eccrine adenocarcinoma XH6Z69 Ceruminous adenocarcinoma XH9C82 Malignant neoplasm arising from pre-existing spiradenoma XH2ZK9 Malignant neoplasm arising from pre-existing cylindroma XH9NW9 Malignant neoplasm arising from pre-existing spiradenocylindroma XH65F9 Sialadenoma papilliferum XH0BE5 Syringocystadenocarcinoma papilliferum XH70J2 Adenoid basal carcinoma XH45F3 Basal cell carcinoma, fibroepithelial XH4GJ2 Basal cell carcinoma, micronodular XH2CR0 Basal cell carcinoma, nodular XH2615 Basal cell carcinoma, NOS XH4C18 Basosquamous carcinoma XH5VK4 Infiltrating basal cell carcinoma, NOS XH0T12 Infiltrating basal cell carcinoma, non-sclerosing XH67Y4 Infiltrating basal cell carcinoma, sclerosing XH9E93 Metatypical carcinoma XH5NL6 Superficial basal cell carcinoma XH2HE7 Pigmented basal cell carcinoma XH9K96 Trichilemmocarcinoma XH9G49 Pilomatrical carcinoma XH6S67 Basal cell carcinoma with adnexal differentiation XH3DL9 Trichoblastic carcinoma XH8324 Trichoblastic carcinosarcoma XH1JH6 Basal cell carcinoma, sarcomatoid XH4E71 Haemangioendothelioma, malignant XH6264 Hemangiosarcoma XH36A5 Kaposi sarcoma XH6FJ5 Kupffer cell sarcoma XH3C78 Intravascular bronchial alveolar tumour XH36H7 Intimal sarcoma XH9GF8 Epithelioid haemangioendothelioma, NOS XH2PY4 Adenocarcinoma with squamous metaplasia XH7873 Adenosquamous carcinoma XH9JP2 Epithelial-myoepithelial carcinoma XH7247 Adenocarcinoma with cartilaginous and osseous metaplasia XH2QL8 Adenocarcinoma with spindle cell metaplasia XH6G98 Fibromatosis-like metaplastic carcinoma XH4GA3 Adenocarcinoma with apocrine metaplasia XH4T39 Adenocarcinoma with neuroendocrine differentiation XH0RD4 Metaplastic carcinoma, NOS XH7MV6 Hepatoid adenocarcinoma XH95Y6 Squamoid eccrine ductal carcinoma XH8XD1 Endometrioid carcinoma with squamous differentiation XH5544 Adenosarcoma XH1YV7 Carcinofibroma XH42V2 Carcinoma ex pleomorphic adenoma XH2RK1 Carcinosarcoma, embryonal XH2CV3 Endometrial stromal sarcoma, high grade XH1S94 Endometrial stromal sarcoma, low grade XH9HQ1 Gastrointestinal stromal tumour XH2WE3 Hepatoblastoma XH0765 Clear cell sarcoma of kidney XH64D5 Malignant chondroid syringoma XH9M31 Malignant cystic nephroma XH3RF3 Rhabdoid tumor, NOS XH0Y65 Mesodermal mixed tumour XH7ZJ9 Mullerian mixed tumour XH27L5 Pancreatoblastoma XH2FY9 Pleuropulmonary blastoma XH5VH1 Pulmonary blastoma XH1TK5 Endometrial stromal sarcoma, NOS XH49Y5 Stromal sarcoma, NOS XH0V86 Mixed tumour, malignant, NOS XH5QN3 Nephroblastoma, NOS XH0H07 Hepatoblastoma, epithelioid XH33R5 Hepatoblastoma, mixed epithelial-mesenchymal XH2W45 Carcinosarcoma, NOS XH7TL5 Adenomyoepithelioma with carcinoma XH3B27 Phosphaturic mesenchymal tumour, malignant XH43E6 Myoepithelial carcinoma XH9N95 Mesenchymoma, malignant XH42Q2 Embryonal sarcoma XH4VQ1 Gastroblastoma XH5CT2 Gastrointestinal autonomic nerve tumour XH0712 Gastrointestinal pacemaker cell tumour XH5WU3 Intraductal papillary-mucinous carcinoma, invasive XH2SE1 Intraductal papillary mucinous neoplasm with an associated invasive carcinoma XH0572 Micropapillary serous carcinoma XH5P21 Solid pseudopapillary carcinoma XH0219 Cystadenocarcinoma, NOS XH7A08 Serous carcinoma, NOS XH6JU6 Papillary cystadenocarcinoma, NOS XH12V5 Low grade serous carcinoma XH24N6 High grade serous carcinoma XH1390 Mucinous cystadenocarcinoma, NOS XH1K19 Mucinous cystic tumour with an associated invasive carcinoma XH4186 Seromucinous carcinoma XH1S75 Mucinous adenocarcinoma XH4U83 Pseudomyxoma peritonei with unknown primary site XH5EQ2 Mucinous tubular and spindle cell carcinoma XH83J5 Pseudomyxoma peritonei XH4KC5 Mucinous carcinoma, gastric type XH56K0 Metastatic signet ring cell carcinoma XH5AF5 Mucin-producing adenocarcinoma XH4546 Signet ring cell carcinoma XH2KK0 Poorly cohesive carcinoma XH3RD4 Krukenberg tumour XH0XE5 Signet ring cell/histiocytoid carcinoma XH3AE9 Solid pseudopapillary neoplasm of pancreas XH9HB7 Lobular carcinoma, pleomorphic XH1146 Juvenile carcinoma of breast XH8TH6 Cystic hypersecretory carcinoma XH44J4 Secretory carcinoma XH7KH3 Infiltrating duct carcinoma, NOS XH9FX2 Adenocarcinoma of mammary gland type XH1N58 Comedocarcinoma, NOS XH8MA7 Intraductal papillary adenocarcinoma with invasion XH8KR8 Papillary carcinoma of the breast XH90W1 Intraductal papillary neoplasm with associated invasive carcinoma XH0GT6 Encapsulated papillary carcinoma with invasion XH9C56 Invasive micropapillary carcinoma of breast XH1XB5 Solid papillary carcinoma with invasion XH2YP5 Medullary carcinoma, NOS XH9B99 Medullary-like carcinoma XH2XR3 Lobular carcinoma, NOS XH9620 Medullary adenocarcinoma XH6KZ1 Atypical medullary carcinoma XH6PY4 Duct carcinoma, desmoplastic type XH55H7 Medullary carcinoma with lymphoid stroma XH3RK9 Tubulolobular carcinoma XH0408 Infiltrating ductular carcinoma XH8RN5 Infiltrating duct and lobular carcinoma XH9Z29 Intraductal and lobular carcinoma XH6MH3 Infiltrating duct and lobular carcinoma in situ XH9551 Infiltrating lobular carcinoma and ductal carcinoma in situ XH8CS0 Infiltrating duct mixed with other types of carcinoma XH9GX4 Infiltrating duct and colloid carcinoma XH2ST9 Infiltrating duct and cribriform carcinoma XH3969 Infiltrating duct and mucinous carcinoma XH1ND7 Infiltrating duct and tubular carcinoma XH3CB4 Infiltrating lobular mixed with other types of carcinoma XH5SD5 Polymorphous adenocarcinoma XH9G73 Inflammatory carcinoma XH3E21 Paget disease, mammary XH47A6 Paget disease and infiltrating duct carcinoma of breast XH70F8 Paget disease, extramammary XH0C76 Paget disease and intraductal carcinoma of breast XH32K6 Basal-like carcinoma of breast XH4ZU9 Adenocarcinoma of anogenital mammary-like glands XH5KW8 Carcinoma of male breast XH4EK4 Endocrine mucin-producing sweat gland carcinoma XH56X7 Carcinoma with osteoclast-like giant cells XH63D2 Carcinoma, NOS XH3XZ6 Giant cell and spindle cell carcinoma XH1JZ2 Giant cell carcinoma XH00N7 Glassy cell carcinoma XH4QU2 Large cell carcinoma with rhabdoid phenotype XH0NL5 Large cell neuroendocrine carcinoma XH35G0 Pleomorphic carcinoma XH92T7 Polygonal cell carcinoma XH35M3 Pseudosarcomatous carcinoma XH1YN3 Carcinoma, metastatic, NOS XH8D74 Carcinomatosis XH4P61 Epithelioma, malignant XH45J4 Large cell carcinoma, NOS XH1YY4 Carcinoma, undifferentiated, NOS XH57U9 Carcinoma, anaplastic, NOS XH2855 Nuclear protein in testis (NUT) associated carcinoma XH3RZ4 Spindle cell carcinoma, NOS XH0YB0 Small cell carcinoma, NOS XH9SY0 Small cell neuroendocrine carcinoma XH28J9 Oat cell carcinoma XH3T00 Small cell carcinoma, fusiform cell XH6GK0 Small cell carcinoma, intermediate cell XH8ZR8 Small cell carcinoma, hypercalcaemic type XH7YE3 Combined small cell carcinoma XH0793 Combined small cell-adenocarcinoma XH6FK9 Combined small cell-large cell carcinoma XH9ZD2 Combined small cell-squamous cell carcinoma XH1DU4 Non-small cell carcinoma XH26N1 Heterotopia-associated carcinoma XH90B3 Combined large cell neuroendocrine carcinoma XH98Z7 Anaplastic undifferentiated carcinoma XH5R16 Dedifferentiated carcinoma XH2BS4 Squamous carcinoma with osteoclast-like giant cells XH2224 Undifferentiated carcinoma with osteoclast-like giant cells XH6NJ7 Brenner tumour, malignant XH7284 Mucinous adenocarcinofibroma XH75P5 Periductal stromal tumour, low grade XH9JC2 Serous adenocarcinofibroma XH6PQ0 Serous cystadenocarcinofibroma XH0WW5 Mucinous cystadenocarcinofibroma XH8HJ7 Phyllodes tumour, malignant XH8EV4 Fascial fibrosarcoma XH6LT0 Fibromyxosarcoma XH7BC6 Infantile fibrosarcoma XH3406 Periosteal fibrosarcoma XH56W2 Periosteal sarcoma, NOS XH1HP3 Solitary fibrous tumour, malignant XH4EP1 Fibrosarcoma, NOS XH1DA3 Solitary fibrous tumour/Haemangiopericytoma, grade 3 XH2668 Myofibroblastic sarcoma XH0947 Malignant fibrous histiocytoma XH8WH0 Myxofibrosarcoma XH9V92 Dermatofibrosarcoma protuberans, fibrosarcomatous XH24E0 Dysgerminoma XH0A34 Germ cell tumour, nonseminomatous XH1E13 Germinoma XH7SG5 Hepatoid yolk sac tumour XH0N49 Immature teratoma, malignant XH2PP9 Malignant teratoma, undifferentiated XH9Z28 Polyembryoma XH6YQ4 Seminoma, anaplastic XH80D1 Spermatocytic seminoma XH56W1 Teratocarcinoma XH09W7 Yolk sac tumour XH9FM4 Seminoma, NOS XH8MB9 Embryonal carcinoma, NOS XH15X1 Yolk sac tumour, post pubertal type XH7YZ9 Teratoma, malignant, NOS XH43T4 Malignant teratoma, intermediate XH33E8 Teratoma with malignant transformation XH2PS1 Mixed germ cell tumour XH9QP9 Germ cell tumour with associated haematological malignancy XH5U02 Mixed teratoma and seminoma XH5PU7 Struma ovarii, malignant XH1P78 Teratocarcinosarcoma XH0492 Giant cell tumour of bone, malignant XH84X1 Malignant giant cell tumour of soft parts XH6JN6 Medulloblastoma with extensive nodularity XH85M7 Medulloblastoma, SHH activated, NOS XH8SH6 CNS embryonal tumour, NOS XH89C3 Central primitive neuroectodermal tumour XH3EX1 Medulloblastoma, WNT-activated, classic XH5163 Medulloblastoma, WNT-activated, Large cell type XH2FW8 Medulloblastoma, WNT-activated, Anaplastic type XH1SH4 Medulloblastoma, SHH-activated and TP53-mutant XH87Q5 Medulloblastoma, non-WNT/non-SHH XH51C5 Embryonal tumours with multilayered rosettes with C19MC alteration XH0KZ2 Embryonal tumour with multilayered rosettes, NOS XH5538 Cerebellar sarcoma, NOS XH8R14 Medullomyoblastoma XH7Y86 Supratentorial PNET XH5PR7 Large cell medulloblastoma XH0H95 Anaplastic medulloblastoma XH8UC5 Giant cell glioblastoma XH0RY1 Classic medulloblastoma XH7PN5 Desmoplastic nodular medulloblastoma XH3904 Papillary tumour of the pineal region XH2C49 Diffuse astrocytoma, IDH-wildtype XH2BA5 Epithelioid glioblastoma XH0ZP6 Medulloblastoma, WNT-activated, NOS XH5XD3 Medulloblastoma, group 3 XH25R4 Medulloblastoma, group 4 XH39Z7 Astrocytoma, anaplastic, IDH-wildtype XH17F8 Diffuse low-grade glioma, MAPK pathway-altered XH2SS9 Diffuse hemispheric glioma, H3 G34-mutant XH4Q01 Diffuse paediatric-type high-grade glioma, H3-wildtype and IDH-wildtype XH4ZM8 Infant-type hemispheric glioma XH12D2 Pilocytic astrocytoma – XH29Q5 Pilomyxoid astrocytoma XH1DC5 Astroblastoma XH96C7 Astrocytoma, anaplastic XH1S63 Astrocytoma, low grade XH54D9 Cellular ependymoma XH3M77 Choroid plexus carcinoma XH6E51 Clear cell ependymoma XH8W32 Diffuse astrocytoma XH6UY7 Diffuse astrocytoma, low grade XH6922 Ependymoma, anaplastic XH6C35 Fibrillary astrocytoma XH5Y81 Gemistocytic astrocytoma XH4RQ3 Glioma, malignant XH6ZH4 Gliomatosis cerebri XH9RC8 Gliosarcoma XH6F49 Oligoastrocytoma, NOS XH9J28 Papillary ependymoma XH99U2 Pleomorphic xanthoastrocytoma XH6UV4 Protoplasmic astrocytoma XH4BJ4 Tanycytic ependymoma XH7692 Diffuse midline glioma, H3 K27M-mutant XH9YU2 Diffuse intrinsic pontine glioma, H3 K27M-mutant XH1511 Ependymoma, NOS XH2AY7 Ependymoma, RELA fusion-positive XH6PH6 Astrocytoma, NOS XH36Y8 Cystic astrocytoma XH2HK4 Diffuse astrocytoma, IDH-mutant XH7HQ6 Astrocytoma, anaplastic, IDH-mutant XH83Y5 Polar spongioblastoma XH8BK8 Anaplastic pleomorphic xanthoastrocytoma XH7F82 Glioblastoma, NOS XH5571 Glioblastoma, IDH-wild type XH0MB1 Glioblastoma, primary, NOS XH3N49 Diffuse midline glioma, NOS XH61Y5 Diffuse intrinsic pontine glioma XH4FN3 Glioblastoma, IDH mutant XH17J4 Glioblastoma, secondary, NOS XH7W59 Oligodendroglioma, NOS XH7K31 Oligodendroglioma, IDH-mutant and 1p/19q co deleted XH9QF3 Oligodendroglioma, anaplastic, IDH mutant and 1p/19q co deleted XH7CX7 Oligodendroblastoma XH8P29 Medulloblastoma, NOS XH9M38 Medulloblastoma, SHH-activated and TP53-wild type XH8844 Oligodendroglioma, anaplastic XH4B47 Melanotic medulloblastoma XH8V95 Alveolar soft part sarcoma XH90D3 Granular cell tumour, malignant XH1C03 Dedifferentiated liposarcoma XH6R46 Fibroblastic liposarcoma XH7PE7 Inflammatory liposarcoma XH7Y61 Liposarcoma, well differentiated XH8VG3 Mixed liposarcoma XH3EL0 Myxoid liposarcoma XH25R1 Pleomorphic liposarcoma XH8D43 Sclerosing liposarcoma XH2J05 Liposarcoma, NOS XH10U6 Lymphangiosarcoma XH0324 Meningioma, malignant XH2NY9 Papillary meningioma XH6QS9 Rhabdoid meningioma XH5976 Meningeal sarcomatosis XH71B5 Adenocarcinoma of rete ovarii XH5WG5 Mesonephroma, malignant XH54S8 Fibrous mesothelioma, malignant XH0XV0 Mesothelioma, malignant XH1DX8 Mesothelioma, biphasic, malignant XH0VP5 Epithelioid mesothelioma, malignant XH8F52 Adamantinoma of long bones XH2S71 Mixed pineal tumour XH1S48 Pineal parenchymal tumour of intermediate differentiation XH1ZH1 Pineoblastoma XH3D20 Transitional pineal tumour XH7K24 Neuroectodermal tumour, NOS XH6P76 Peripheral primitive neuroectodermal tumour XH9GH0 Chordoma, NOS XH8KJ8 Ewing sarcoma XH0FH0 Askin tumour XH17D8 Chondroid chordoma XH7303 Dedifferentiated chordoma XH1J36 Mucoepidermoid carcinoma XH27W3 Angiomyosarcoma XH13Z5 Epithelioid leiomyosarcoma XH7ED4 Leiomyosarcoma, NOS XH08B3 Mixed embryonal rhabdomyosarcoma and alveolar rhabdomyosarcoma XH6YL0 Mixed type rhabdomyosarcoma XH8H07 Myosarcoma XH3122 Myxoid leiomyosarcoma XH5SX9 Pleomorphic rhabdomyosarcoma, NOS XH4VB5 Pleomorphic rhabdomyosarcoma, adult type XH0GA1 Rhabdomyosarcoma, NOS XH83G1 Embryonal rhabdomyosarcoma, NOS XH4749 Embryonal rhabdomyosarcoma, pleomorphic XH7V57 Sarcoma botryoides XH7NM2 Spindle cell rhabdomyosarcoma XH7099 Alveolar rhabdomyosarcoma XH0S12 Ectomesenchymoma XH4V76 Low grade fibromyxoid sarcoma XH4BT2 Sclerosing epithelioid fibrosarcoma XH3TB0 Ossifying fibromyxoid tumour, malignant XH51Y9 Pulmonary myxoid sarcoma with EWSR1-CREB1 translocation XH5WF6 Myxosarcoma XH2XP8 Malignant peripheral nerve sheath tumour XH5C30 Melanotic MPNST XH3NT0 Melanotic psammomatous MPNST XH8HF5 MPNST with glandular differentiation XH7HR8 MPNST with mesenchymal differentiation XH3W53 MPNST with perineurial differentiation XH4V81 Malignant peripheral nerve sheath tumour, epithelioid XH88C2 Neurilemoma, malignant XH2VV8 Malignant peripheral nerve sheath tumour with rhabdomyoblastic differentiation XH31C8 Perineurioma, malignant XH7ZQ4 Atypical teratoid/rhabdoid tumour XH2GG3 Ganglioglioma, anaplastic XH77W7 Ganglioneuroblastoma XH0RB7 Ganglioneuroblastoma, intermixed XH6JM6 Retinoblastoma, differentiated XH49K9 Spongioneuroblastoma XH0AM8 Teratoid medulloepithelioma XH70S0 CNS ganglioneuroblastoma XH85Z0 Neuroblastoma, NOS XH2WK5 Medulloepithelioma, NOS XH9FP2 Neuroepithelioma, NOS XH8WC7 Retinoblastoma, NOS XH7KP6 Retinoblastoma, undifferentiated XH1YZ7 Retinoblastoma, diffuse XH09A4 Olfactory neurogenic tumour XH7QE0 Olfactory neurocytoma XH2Y49 Olfactory neuroepithelioma XH50L1 Olfactory neuroblastoma XH3AV2 CNS embryonal tumor with rhabdoid features XH9L11 Acral melanoma XH3TK1 Amelanotic melanoma XH8TE3 Balloon cell melanoma XH1P36 Desmoplastic melanoma, amelanotic XH1Z15 Desmoplastic melanoma, NOS XH9NL4 Lentigo maligna melanoma XH5L25 Malignant melanoma arising in giant congenital naevus XH23B1 Malignant melanoma in junctional naevus XH7L76 Malignant melanoma in precancerous melanosis XH6XP3 Malignant melanoma, regressing XH1BP7 Meningeal melanomatosis XH5QP3 Mucosal lentiginous melanoma XH5F94 Neurotropic melanoma, malignant XH4QG5 Nodular melanoma XH08X7 Superficial spreading melanoma XH4846 Malignant melanoma, NOS XH25M1 Spindle cell melanoma, NOS XH8HA2 Mixed epithelioid and spindle cell melanoma XH0QL5 Epithelioid cell melanoma XH5KW3 Spindle cell melanoma, type A XH5YE7 Spindle cell melanoma, type B XH1G74 Blue naevus, malignant XH7JW1 Low cumulative sun damage melanoma XH8DS3 Malignant Spitz tumour XH3DN1 Melanoma, meningeal XH8681 Nevoid melanoma XH1MW0 Ameloblastic odontosarcoma XH96J9 Ameloblastoma, metastasizing XH4M89 Odontogenic tumour, malignant XH0XD5 Ameloblastic fibrosarcoma XH4LP1 Odontogenic carcinosarcoma XH2BX2 Ghost cell odontogenic carcinoma XH5DZ4 Clear cell odontogenic carcinoma XH1Y90 Central osteosarcoma XH3T03 Chondroblastic osteosarcoma XH23T4 Fibroblastic osteosarcoma XH29N8 Fibrochondrosarcoma XH6TL0 High grade surface osteosarcoma XH9LS2 Intracortical osteosarcoma XH9119 Intraosseous well differentiated osteosarcoma XH06W9 Osteosarcoma in Paget disease of bone XH8HG5 Parosteal osteosarcoma XH48A9 Periosteal osteosarcoma XH4EZ4 Small cell osteosarcoma XH5CL5 Telangiectatic osteosarcoma XH1XF3 Osteosarcoma, NOS XH2CD6 Osteosarcoma, extraskeletal XH7N84 Low grade central osteosarcoma XH8J23 Chondrosarcoma, NOS XH6LT5 Chondrosarcoma, grade 2 XH0Y34 Chondrosarcoma, grade 3 XH5FH4 Juxtacortical chondrosarcoma XH1S32 Periosteal chondrosarcoma XH6W00 Chondroblastoma, malignant XH9344 Myxoid chondrosarcoma XH8X47 Mesenchymal chondrosarcoma XH7XB9 Clear cell chondrosarcoma XH6E77 Dedifferentiated chondrosarcoma XH9WD1 Perivascular epithelioid tumour, malignant XH1UN6 Extra-adrenal paraganglioma XH8GG7 Nonchromaffin paraganglioma XH05Y1 Glomangiosarcoma XH21E6 Glomus tumour, malignant XH9YX6 Middle ear paraganglioma XH5521 Laryngeal paraganglioma XH1493 Vagal paraganglioma XH3JF3 Composite paraganglioma XH9K97 Composite pheochromocytoma XH0EW6 Paraganglioma, NOS XH4G21 Sympathetic paraganglioma XH5LK3 Parasympathetic paraganglioma XH7YU4 Aortic body tumour XH3FS7 Carotid body paraganglioma XH20B4 Chemodectoma XH3854 Pheochromocytoma, NOS XH4UM7 Sarcoma, NOS XH7Y17 Sarcomatosis, NOS XH7AN8 Spindle cell sarcoma XH73J4 Giant cell sarcoma XH85G7 Small cell sarcoma XH4F96 Epithelioid sarcoma XH6HY6 Undifferentiated sarcoma XH5SN6 Desmoplastic small round cell tumour XH7XH3 Pleomorphic dermal sarcoma XH92Y0 Epithelioid sarcoma, undifferentiated XH44E8 Androblastoma, malignant XH1QG7 Granulosa cell carcinoma XH97Z8 Granulosa cell tumour, sarcomatoid XH29E0 Sertoli-Leydig cell tumour, poorly differentiated XH3BT2 Sertoli-Leydig cell tumour, poorly differentiated, with heterologous elements XH4KB9 Sertoli-Leydig cell tumour, sarcomatoid XH1JS6 Thecoma, malignant XH0GA5 Adult granulosa cell tumor of ovary XH7DV5 Granulosa cell tumour, adult type XH9G68 Leydig cell tumour, malignant XH4L39 Steroid cell tumour, malignant XH7051 Sertoli cell carcinoma XH3GS1 Basaloid squamous cell carcinoma XH0UU4 Papillary carcinoma, NOS XH6S97 Papillary squamous cell carcinoma XH7LH0 Squamous cell carcinoma, adenoid XH9DC1 Squamous cell carcinoma, clear cell type XH4CR9 Squamous cell carcinoma, keratinizing, NOS XH84Q4 Squamous cell carcinoma, metastatic, NOS XH90Y3 Squamous cell carcinoma, microinvasive XH0945 Squamous cell carcinoma, NOS XH2435 Squamous cell carcinoma, small cell, nonkeratinizing XH6D80 Squamous cell carcinoma, spindle cell XH5PM0 Verrucous carcinoma, NOS XH7UR7 Warty carcinoma XH6705 Squamous cell carcinoma, large cell, nonkeratinizing, NOS XH2JN3 Squamous cell carcinoma with horn formation XH1E40 Lymphoepithelial carcinoma XH4GV2 Schmincke tumour XH0Z16 Pseudovascular squamous cell carcinoma XH24M0 Papillary-basaloid carcinoma XH0EJ7 Squamous cell carcinoma, HPV positive XH2137 Squamous cell carcinoma, HPV negative XH6FU0 Warty-basaloid carcinoma XH9XR8 Keratoacanthoma XH9B22 Synovial sarcoma, NOS XH77N6 Clear cell sarcoma, NOS XH9346 Synovial sarcoma, spindle cell XH06L8 Synovial sarcoma, epithelioid cell XH1J28 Synovial sarcoma, biphasic XH3797 Biphenotypic sinonasal sarcoma XH5854 Malignant melanoma of soft parts XH6WN9 Thymoma, type A XH0JH0 Thymoma, type AB XH66U8 Thymoma, type B1 XH2G89 Thymoma, type B2 XH4EW9 Thymoma, type B3 XH3734 Thymoma, NOS XH1GA4 Intrapulmonary thymoma XH6QN6 Sclerosing thymoma XH3DX0 Metaplastic thymoma XH6AK2 Thymic carcinoma, NOS XH6ZG8 Spindle epithelial tumour with thymus-like element XH33N4 Intrathyroid thymic carcinoma XH4UA2 Cylindrical cell carcinoma XH35M0 Schneiderian carcinoma XH8EH1 Transitional cell carcinoma, NOS XH7TL4 Transitional carcinoma XH5P27 Urothelial carcinoma, sarcomatoid XH0NZ4 Papillary urothelial carcinoma XH08S6 Transitional cell carcinoma, micropapillary XH3UJ1 Cloacogenic carcinoma XH2V80 Basaloid carcinoma XH4W76 Urothelial carcinoma, micropapillary XH3WM1 Choriocarcinoma combined with other germ cell elements XH0774 Malignant teratoma, trophoblastic XH8PK7 Choriocarcinoma, NOS XH8FW3 Trophoblastic tumour, epithelioid XH2N45 Myelodysplastic syndrome with single lineage dysplasia XH5B21 Myelodysplastic syndrome with ring sideroblasts and single lineage dysplasia XH79X8 Myelodysplastic syndrome with excess blasts XH1D20 Refractory anaemia with excess blasts in transformation XH5DA2 Myelodysplastic syndrome with multilineage dysplasia XH3T02 Myelodysplastic syndrome with isolated del (5q) XH0L58 Therapy-related myelodysplastic syndrome, NOS XH7PK9 Myelodysplastic syndrome, NOS XH8BA8 Myelodysplastic syndrome with ring sideroblasts and multilineage dysplasia XH3EJ1 Myeloproliferative neoplasm, unclassifiable XH28M3 Myelodysplastic/myeloproliferative neoplasm, unclassifiable XH0453 Polycythaemia vera XH5HH7 Myeloproliferative neoplasm, NOS XH7GG7 Primary myelofibrosis XH4ZM5 Essential thrombocythemia XH5NQ7 Chronic neutrophilic leukaemia XH51D2 Chronic eosinophilic leukaemia XH07H5 Myeloid and lymphoid neoplasms with PDGFRA rearrangement XH6QD4 Myeloid neoplasms with PDGFRB rearrangement XH1WR8 Myeloid and lymphoid neoplasms with FGFR1 abnormalities XH2WB4 Myeloid or lymphoid neoplasm with PCM1-JAK2 XH4S92 Leukaemia, NOS XH29P0 Aleukemic leukaemia, NOS XH80C3 Chronic leukaemia, NOS XH6QV5 Subacute leukaemia, NOS XH1B20 Acute leukaemia, NOS XH37U0 Acute biphenotypic leukaemia XH2H98 Acute bilineal leukaemia XH3VV7 Acute mixed lineage leukaemia XH97B7 Mixed phenotype acute leukaemia with t(9;22)(q34;q11.2); BCR-ABL1 XH2S51 Mixed phenotype acute leukaemia with t(v;11q23); MLL rearranged XH1928 Mixed phenotype acute leukaemia, B/myeloid, NOS XH4YB5 Mixed phenotype acute leukaemia, T/myeloid, NOS XH81V3 B lymphoblastic leukaemia/lymphoma, NOS XH73L9 B lymphoblastic leukaemia/lymphoma with t(9;22)(q34;q11.2); BCR-ABL1 XH8GG0 B lymphoblastic leukaemia/lymphoma with t(v;11q23); MLL rearranged XH4KA2 B lymphoblastic leukaemia/lymphoma with t(12;21)(p13;q22); TEL-AML1 (ETV6-RUNX1) XH24C7 B lymphoblastic leukaemia/lymphoma with hyperdiploidy XH2MD9 B lymphoblastic leukaemia/lymphoma with hypodiploidy (Hypodiploid ALL) XH4ZL2 B lymphoblastic leukaemia/lymphoma with t(5;14)(q31;q32); IL3-IGH XH3GU8 B lymphoblastic leukaemia/lymphoma with t(1;19)(q23;p13.3); E2A-PBX1 (TCF3-PBX1) XH7Q12 Lymphoid leukaemia, NOS XH1GQ1 Lymphatic leukaemia, NOS XH7PW5 Lymphocytic leukaemia, NOS XH4KS4 Aleukemic lymphoid leukaemia XH5BA6 Lymphosarcoma cell leukaemia XH8GQ0 Subacute lymphoid leukaemia XH15T2 B-cell chronic lymphocytic leukaemia/small lymphocytic lymphoma XH6TE2 Adult T-cell leukaemia/lymphoma (HTLV-1 positive) XH6687 T-cell large granular lymphocytic leukaemia XH5EN4 Chronic lymphoproliferative disorder of NK cells XH8TD6 Prolymphocytic leukaemia, NOS XH95H2 Prolymphocytic leukaemia, B-cell type XH0DU4 Prolymphocytic leukaemia, T-cell type XH5J37 Precursor cell lymphoblastic leukaemia, NOS XH7T28 Precursor T-cell lymphoblastic leukaemia XH50W7 T lymphoblastic leukaemia/lymphoma XH1D04 B lymphoblastic leukemia/lymphoma, BCR-ABL1-like XH0KD4 B lymphoblastic leukemia/lymphoma with iAMP21 XH8F29 Early T-cell precursor acute lymphoblastic leukemia XH0E35 Chronic monocytic leukaemia XH6JX2 Eosinophilic leukaemia XH5JT8 Monocytic leukaemia, NOS XH1S60 Subacute monocytic leukaemia XH7DF6 Subacute myeloid leukaemia XH8AA5 Acute myeloid leukaemia, NOS XH4M02 Acute myeloid leukemia with biallelic mutation of CEBPA XH74W8 Acute myeloid leukaemia with mutated NPM1 XH4XG8 Chronic myeloid leukaemia, NOS XH9Y46 Acute myeloid leukaemia with t(6;9)(p23;q34); DEK-NUP214 XH1A50 Acute promyelocytic leukaemia, t(15;17)(q22;q11-12) XH78Y4 Acute myelomonocytic leukaemia XH2KE3 Acute myeloid leukaemia with inv(3)(q21;q26.2) or t(3.3)(q21;q26.2); RPN1-EVI1 XH7MR1 Acute basophilic leukaemia XH3PA4 Acute myeloid leukaemia with abnormal marrow eosinophils XH90G0 Acute myeloid leukaemia, minimal differentiation XH5AH8 Acute myeloid leukaemia without maturation XH1XJ9 Acute myeloid leukaemia with maturation XH2AB7 Chronic myelogenous leukaemia, BCR/ABL positive XH21X5 Atypical chronic myeloid leukaemia, BCR/ABL negative XH26U9 Atypical chronic myeloid leukaemia, Philadelphia chromosome (Ph1) negative XH9NE2 Acute monocytic leukaemia XH1K97 Acute monoblastic and monocytic leukaemia XH64R4 Acute myeloid leukaemia with myelodysplasia-related changes XH3CX5 Acute myeloid leukaemia, t(8;21)(q22;q22) XH1E41 Acute myeloid leukaemia, 11q23 abnormalities XH6AQ7 Myeloid leukaemia associated with Down Syndrome XH4750 Acute megakaryoblastic leukaemia XH16K4 Acute myeloid leukaemia (megakaryoblastic) with t(1;22)(p13;q13); RBM15-MKL1 XH7045 Therapy related myeloid neoplasm XH6Z50 Therapy-related acute myeloid leukaemia, alkylating agent related XH4EJ0 Therapy-related acute myeloid leukaemia, epipodophyllotoxin-related XH3L40 Myeloid sarcoma XH1075 Acute panmyelosis with myelofibrosis XH6FZ7 Acute myeloid leukemia with BCR-ABL1 XH1EK4 Acute myeloid leukemia with mutated RUNX1 XH43N4 Acute erythroid leukemia XH7S21 Myeloid leukaemia, NOS XH7LG8 Aleukemic myeloid leukaemia XH5DV4 Aleukemic monocytic leukaemia XH86N4 Chronic myelomonocytic leukaemia, NOS XH0FC4 Chronic myelomonocytic leukaemia, Type I XH7HJ7 Chronic myelomonocytic leukaemia, Type II XH4QZ1 Juvenile myelomonocytic leukaemia XH9MA0 Aggressive NK-cell leukaemia XH5J10 Hairy cell leukaemia XH4KF3 Immunoproliferative disease, NOS XH8GW4 Waldenstrom macroglobulinemia XH7RJ1 Heavy chain disease, NOS XH1Y65 Alpha heavy chain disease XH1EA7 Gamma heavy chain disease XH2JK2 Mu heavy chain disease XH3SS7 Immunoproliferative small intestinal disease XH71D5 Lymphomatoid granulomatosis, grade 3 XH6A72 Mast cell sarcoma XH2992 Malignant mastocytosis XH10N1 Aggressive systemic mastocytosis XH1H01 Systemic mastocytosis with AHNMD XH5191 Systemic mastocytosis with associated haematological clonal non-mast cell disorder XH5ER6 Mast cell leukaemia XH1VJ3 Erdheim-Chester disease Has manifestation - multiple selections are allowed [select] MG30.10 Chronic cancer pain Has severity - only one may be selected [select] XS1G Stage I XS4P Stage II XS6H Stage III XS9R Stage IV Has alternative severity1 - only one may be selected [select] XS56 Grade I XS58 Grade II XS7Z Grade III XS7M Grade IV XS7H Undetermined grade Has alternative severity2 - only one may be selected [select] XS0J A Remission / Free of disease XS05 B Local Disease – XS0E Local limited – XS67 Locally advanced XS9S C Regional disease XS4Z D Distant disease
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