4A40.0 Systemic lupus erythematosus International Classification of Diseases for Mortality and Morbidity Statistics, 11th Revision, v2024-01 Systemic lupus erythematosus (SLE) is a clinically multisystem disease, which is autoimmune in origin and is characterised by the presence of autoantibodies directed against nuclear antigens. Manifestations include rash, arthritis and fatigue, nephritis, neurological problems, anaemia and thrombocytopenia at the more severe end of the spectrum.
sections/codes in this section (4A40.0-4A40.0) postcoordination Add Stem and/or Extension codes to form a cluster code which adds detail to the condition.
Has manifestation - multiple selections are allowed [select] 3A00 Iron deficiency anaemia – 3A00.0 Acquired iron deficiency anaemia due to blood loss – 3A00.1 Acquired iron deficiency anaemia due to low intake – 3A00.2 Acquired iron deficiency anaemia due to decreased absorption – 3A00.3 Acquired iron deficiency anaemia due to increased requirement – 3A00.Y Other specified iron deficiency anaemia – 3A00.Z Iron deficiency anaemia, unspecified –– 3A00.01 Chronic posthaemorrhagic anaemia –– 3A00.0Z Acquired iron deficiency anaemia due to blood loss, unspecified 3A01 Megaloblastic anaemia due to vitamin B12 deficiency – 3A01.0 Hereditary vitamin B12 deficiency anaemia – 3A01.1 Neonatal vitamin B12 deficiency anaemia – 3A01.2 Vitamin B12 deficiency anaemia due to low intake – 3A01.3 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency – 3A01.4 Vitamin B12 deficiency anaemia due to intestinal disease – 3A01.5 Drug-induced vitamin B12 deficiency anaemia – 3A01.Y Other specified megaloblastic anaemia due to vitamin B12 deficiency – 3A01.Z Megaloblastic anaemia due to vitamin B12 deficiency, unspecified –– 3A01.30 Pernicious anaemia –– 3A01.3Y Other specified vitamin B12 deficiency anaemia due to intrinsic factor deficiency 3A02 Folate deficiency anaemia – 3A02.0 Hereditary folate deficiency anaemia – 3A02.1 Folate deficiency anaemia due to low intake – 3A02.2 Folate deficiency anaemia due to increased requirements – 3A02.3 Folate deficiency anaemia due to decreased intestinal absorption – 3A02.4 Drug-induced folate deficiency anaemia – 3A02.Y Other specified folate deficiency anaemia – 3A02.Z Folate deficiency anaemia, unspecified 3A03 Other nutritional or metabolic anaemias – 3A03.0 Hereditary orotic aciduria – 3A03.1 Protein deficiency anaemia – 3A03.2 Scorbutic anaemia – 3A03.3 Copper deficiency anaemia – 3A03.4 Acquired other vitamin B deficiency anaemia – 3A03.5 Acquired vitamin A deficiency anaemia – 3A03.6 Acquired vitamin E deficiency anaemia – 3A03.Y Other and unspecified nutritional or metabolic anaemia –– 3A03.40 Acquired pyridoxine deficiency anaemia –– 3A03.41 Acquired riboflavin deficiency anaemia –– 3A03.42 Acquired thiamine deficiency anaemia –– 3A03.4Y Other specified acquired other vitamin B deficiency anaemia – 3A10 Hereditary haemolytic anaemia –– 3A10.0 Haemolytic anaemias due to hexose monophosphate shunt or glutathione metabolism anomalies –– 3A10.1 Haemolytic anaemia due to adenosine deaminase excess –– 3A10.2 Hereditary elliptocytosis –– 3A10.3 Familial pseudohyperkalaemia –– 3A10.Y Other specified hereditary haemolytic anaemia –– 3A10.Z Hereditary haemolytic anaemia, unspecified ––– 3A10.00 Haemolytic anaemia due to glucose-6-phosphate dehydrogenase deficiency ––– 3A10.0Y Other specified haemolytic anaemias due to hexose monophosphate shunt or glutathione metabolism anomalies ––– 3A10.0Z Haemolytic anaemias due to hexose monophosphate shunt or glutathione metabolism anomalies, unspecified – 3A1Y Other specified congenital haemolytic anaemia – 3A20 Acquired haemolytic anaemia, immune –– 3A20.0 Autoimmune haemolytic anaemia, warm type –– 3A20.1 Autoimmune haemolytic anaemia, cold type –– 3A20.2 Autoimmune haemolytic anaemia, mixed type, cold and warm –– 3A20.3 Paroxysmal cold haemoglobinuria –– 3A20.4 Alloimmune haemolytic anaemia –– 3A20.5 Evans syndrome –– 3A20.Y Other specified acquired haemolytic anaemia, immune – 3A21 Acquired haemolytic anaemia, non-immune –– 3A21.0 Paroxysmal nocturnal haemoglobinuria –– 3A21.1 Microangiopathic haemolytic anaemia –– 3A21.2 Haemolytic uraemic syndrome –– 3A21.Y Other specified acquired haemolytic anaemia, non-immune – 3A2Z Acquired haemolytic anaemia, unspecified 3A4Z Haemolytic anaemias, unspecified 3A50 Thalassaemias 3A50.0 Alpha thalassaemia 3A50.1 Alpha thalassaemia related syndromes 3A50.2 Beta thalassaemia 3A50.3 Delta, delta-beta or gamma-delta-beta thalassaemia 3A50.4 Hereditary persistence of fetal haemoglobin 3A50.Y Other specified thalassaemias 3A50.Z Thalassaemias, unspecified – 3A50.00 Mild alpha thalassaemia diseases – 3A50.01 Thalassaemic alpha-chain variants – 3A50.02 Haemoglobin H disease (– α/– – included) – 3A50.03 Homozygous or compound heterozygous alpha0 thalassaemia – 3A50.0Y Other specified alpha thalassaemia – 3A50.0Z Alpha thalassaemia, unspecified 3A51 Sickle cell disorders or other haemoglobinopathies 3A51.0 Sickle cell trait 3A51.1 Sickle cell disease without crisis 3A51.2 Sickle cell disease with crisis 3A51.3 Compound heterozygous sickling disorders without crisis 3A51.4 Compound heterozygous sickling disorders with crisis 3A51.5 Haemoglobin C disease 3A51.6 Haemoglobin D disease 3A51.7 High affinity haemoglobin 3A51.8 Low affinity haemoglobin 3A51.9 Haemoglobin O disease 3A51.A Haemoglobin E disease 3A51.B Haemoglobin C/beta thalassaemia compound heterozygosity 3A51.Y Other specified sickle cell disorders or other haemoglobinopathies 3A51.Z Sickle cell disorders or other haemoglobinopathies, unspecified 3A60 Congenital pure red cell aplasia – 3A60.0 Congenital non-inherited pure red cell aplasia – 3A60.1 Hereditary pure red cell aplasia – 3A60.Z Congenital pure red cell aplasia, unspecified 3A61 Acquired pure red cell aplasia – 3A61.0 Acute acquired pure red cell aplasia – 3A61.1 Chronic acquired pure red cell aplasia – 3A61.Y Other specified acquired pure red cell aplasia – 3A61.Z Acquired pure red cell aplasia, unspecified 3A6Z Pure red cell aplasia, unspecified 3A70 Aplastic anaemia 3A70.0 Congenital aplastic anaemia 3A70.1 Acquired aplastic anaemias 3A70.Z Aplastic anaemia, unspecified – 3A70.10 Drug-induced aplastic anaemia – 3A70.11 Aplastic anaemia due to other external agents – 3A70.12 Idiopathic aplastic anaemia – 3A70.1Y Other specified acquired aplastic anaemias – 3A70.1Z Acquired aplastic anaemias, unspecified 3A71 Anaemia due to chronic disease 3A71.0 Anaemia in neoplastic disease 3A71.1 Anaemia in chronic infectious diseases 3A71.2 Anaemia in chronic kidney disease 3A71.Y Anaemia due to other specified chronic disease 3A71.Z Anaemia due to chronic disease, unspecified 3A72 Sideroblastic anaemia 3A72.0 Congenital sideroblastic anaemias 3A72.1 Acquired sideroblastic anaemias 3A72.Z Sideroblastic anaemia, unspecified – 3A72.00 Hereditary sideroblastic anaemias – 3A72.01 Hereditary syndromic sideroblastic anaemia – 3A72.0Y Other specified congenital sideroblastic anaemias – 3A72.0Z Congenital sideroblastic anaemias, unspecified 3A73 Congenital dyserythropoietic anaemia 3A80 Congenital polycythaemia – 3A80.0 Primary inherited erythrocytosis – 3A80.Y Other specified congenital polycythaemia – 3A80.Z Congenital polycythaemia, unspecified 3A81 Acquired polycythaemia – 3A81.0 Polycythaemia due to hypoxia, including high altitude – 3A81.1 Polycythaemia due to over-transfusion or blood doping – 3A81.2 Relative polycythaemia – 3A81.Y Other specified acquired polycythaemia – 3A81.Z Acquired polycythaemia, unspecified 3A8Z Polycythaemia, unspecified 3A90 Anaemia due to acute disease 3A91 Congenital methaemoglobinaemia 3A92 Hereditary methaemoglobinaemia 3A93 Acquired methaemoglobinaemia 3A94 Acute posthaemorrhagic anaemia 3A9Y Other specified anaemias or erythrocyte disorders 3A9Z Anaemias or other erythrocyte disorders, unspecified – 4A43.21 Secondary Sjögren syndrome 4A44 Vasculitis 4A44.0 Rhizomelic pseudopolyarthritis 4A44.1 Aortic arch syndrome 4A44.2 Giant cell arteritis 4A44.3 Single organ vasculitis 4A44.4 Polyarteritis nodosa 4A44.5 Mucocutaneous lymph node syndrome 4A44.6 Sneddon syndrome 4A44.7 Primary angiitis of the central nervous system 4A44.8 Thromboangiitis obliterans 4A44.9 Immune complex small vessel vasculitis 4A44.A Antineutrophil cytoplasmic antibody-associated vasculitis 4A44.B Leukocytoclastic vasculitis 4A44.Y Other specified vasculitis 4A44.Z Vasculitis, unspecified – 4A44.90 Cryoglobulinaemic vasculitis – 4A44.91 Hypocomplementaemic urticarial vasculitis – 4A44.92 IgA vasculitis – 4A44.9Y Other specified immune complex small vessel vasculitis – 4A44.9Z Immune complex small vessel vasculitis, unspecified – 4A44.A0 Microscopic polyangiitis – 4A44.A1 Granulomatosis with polyangiitis – 4A44.A2 Eosinophilic granulomatosis with polyangiitis – 4A44.AY Other specified antineutrophil cytoplasmic antibody-associated vasculitis – 4A44.AZ Antineutrophil cytoplasmic antibody-associated vasculitis, unspecified – 4A44.B0 Cutaneous leukocytoclastic vasculitis – 4A44.BY Other specified leukocytoclastic vasculitis – 4A44.BZ Leukocytoclastic vasculitis, unspecified – 5A03.2 Autoimmune thyroiditis –– 5A03.20 Hashimoto thyroiditis –– 5A03.21 Painless thyroiditis –– 5A03.2Y Other specified autoimmune thyroiditis –– 5A03.2Z Autoimmune thyroiditis, unspecified 8C81 Autoimmune myopathy 8E4A.0 Paraneoplastic or autoimmune disorders of the central nervous system, brain or spinal cord 9A75 Autoimmune keratitis – 9B71.5 Autoimmune retinopathy BB01.0 Pulmonary arterial hypertension BB20.Y Other specified acute pericarditis BB40 Acute or subacute infectious endocarditis BB41 Myoendocarditis BB42 Periendocarditis BB4Y Other specified acute or subacute endocarditis BB4Z Acute or subacute endocarditis, unspecified BC42 Myocarditis BC42.0 Giant cell myocarditis BC42.1 Infectious myocarditis BC42.2 Hypersensitivity myocarditis BC42.3 Rheumatic myocarditis BC42.Y Other specific myocarditis BC42.Z Myocarditis, unspecified BC42.Y Other specific myocarditis CB05.1 Interstitial lung diseases associated with connective tissue diseases – DA42.0 Autoimmune gastritis DA96 Intestinal malabsorption or protein-losing enteropathy DA96.0 Intestinal malabsorption DA96.1 Protein-losing enteropathy DA96.Y Other specified intestinal malabsorption or protein-losing enteropathy DA96.Z Intestinal malabsorption or protein-losing enteropathy, unspecified – DA96.00 Bacterial overgrowth syndrome – DA96.01 Tropical sprue – DA96.02 Malabsorption or intolerance of specific nutrients – DA96.04 Short bowel syndrome – DA96.05 Intestinal failure – DA96.0Y Other specified intestinal malabsorption – DA96.0Z Intestinal malabsorption, unspecified DB96 Autoimmune liver disease DB96.0 Autoimmune hepatitis DB96.1 Primary biliary cholangitis DB96.2 Primary sclerosing cholangitis DB96.Y Other specified autoimmune liver disease DB96.Z Autoimmune liver disease, unspecified – DB96.10 Primary biliary cholangitis with overlap syndrome – DB96.1Y Other specified primary biliary cholangitis – DB96.1Z Primary biliary cholangitis, unspecified – DB96.20 Primary sclerosing cholangitis with cirrhosis – DB96.2Y Other specified primary sclerosing cholangitis – DB96.2Z Primary sclerosing cholangitis, unspecified DC33 Autoimmune pancreatitis FB30 Infectious myositis FB31 Calcification or ossification of muscle – FB31.0 Progressive osseous heteroplasia – FB31.1 Fibrodysplasia ossificans progressiva – FB31.Y Other specified calcification or ossification of muscle – FB31.Z Calcification or ossification of muscle, unspecified FB32 Certain specified disorders of muscle – FB32.0 Diastasis of muscle – FB32.1 Spontaneous rupture of muscle – FB32.2 Ischaemic infarction of muscle – FB32.3 Immobility syndrome – FB32.4 Contracture of muscle – FB32.5 Muscle strain or sprain – FB32.Y Other specified disorders of muscles –– FB32.20 Idiopathic rhabdomyolysis –– FB32.2Y Other specified ischaemic infarction of muscle –– FB32.2Z Ischaemic infarction of muscle, unspecified FB33 Secondary disorders of muscle FB3Z Disorders of muscles, unspecified GB40 Nephritic syndrome GB41 Nephrotic syndrome GB42 Persistent proteinuria or albuminuria – GB42.0 Albuminuria, Grade A2 – GB42.1 Albuminuria, Grade A3 – GB42.Y Other specified persistent proteinuria or albuminuria – GB42.Z Persistent proteinuria or albuminuria, unspecified GB4Y Other specified glomerular diseases GB4Z Glomerular diseases, unspecified ––– MG30.30 Chronic secondary musculoskeletal pain from persistent inflammation
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