2B5B Gastrointestinal stromal tumour, primary site

International Classification of Diseases for Mortality and Morbidity Statistics, 11th Revision, v2025-01

This is the most common mesenchymal tumour that arises in the gastrointestinal tract. It is generally immunohistochemically positive for CD117 (KIT), phenotypically paralleling Cajal-cell differentiation, and most examples contain KIT- or PDGFRA-activating mutations. It is most frequent in the stomach and to a lesser degree in the small intestine. The prognosis depends on the tumour size and the mitotic activity.

sections/codes in this section ()

• Gastrointestinal stromal tumour of stomach  (2B5B.0)
• Gastrointestinal stromal tumour of small intestine  (2B5B.1)
• Gastrointestinal stromal tumour of other gastrointestinal sites  (2B5B.Y)
• Gastrointestinal stromal tumour of unspecified gastrointestinal sites  (2B5B.Z)

postcoordination

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