Coding experts Alicia and Laureen from CCO review the new 2025 ICD-10-CM code changes.
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2B5B Gastrointestinal stromal tumour, primary site International Classification of Diseases for Mortality and Morbidity Statistics, 11th Revision, v2024-01 This is the most common mesenchymal tumour that arises in the gastrointestinal tract. It is generally immunohistochemically positive for CD117 (KIT), phenotypically paralleling Cajal-cell differentiation, and most examples contain KIT- or PDGFRA-activating mutations. It is most frequent in the stomach and to a lesser degree in the small intestine. The prognosis depends on the tumour size and the mitotic activity.
sections/codes in this section (2B5B-2B5B) postcoordination Add Stem and/or Extension codes to form a cluster code which adds detail to the condition.
Specific anatomy - multiple selections are allowed [select] XA9607 Gastrointestinal tract – XA0828 Oesophagus –– XA1180 Upper third of oesophagus –– XA2BY3 Middle third of oesophagus –– XA9CB6 Lower third of oesophagus –– XA0N03 Cervical oesophagus –– XA8JT3 Thoracic oesophagus –– XA0TN5 Abdominal oesophagus –– XA4YW8 Overlapping sites of oesophagus – XA7SR6 Cardioesophageal junction – XA7MC7 Stomach –– XA2828 Gastric cardia –– XA7UE1 Gastric corpus –– XA56K7 Gastric fundus –– XA6P89 Gastric pylorus ––– XA4EC5 Pyloric antrum –– XA7WQ5 Greater curvature of stomach –– XA4ML9 Lesser curvature of stomach – XA6452 Small intestine –– XA9780 Duodenum –– XA8UM1 Jejunum –– XA0QT6 Ileum – XA1B13 Large intestine –– XA6J68 Caecum –– XA03U9 Colon ––– XA3AL5 Ascending colon ––– XA95L3 Hepatic flexure of colon ––– XA49U1 Transverse colon ––– XA1PY9 Splenic flexure of colon ––– XA2G13 Descending colon ––– XA8YJ9 Sigmoid colon ––– XA33J5 Rectosigmoid junction ––– XA7177 Descending colon and splenic flexure of colon ––– XA25P9 Ascending colon and right flexure of colon –– XA4KU2 Rectum –– XA0D34 Anus –– XA39S6 Anal Canal –– XA8QB7 Cloacogenic zone – XA28R6 Upper gastrointestinal tract, not elsewhere classified – XA8PW4 Appendix – XA0828 Oesophagus –– XA1180 Upper third of oesophagus –– XA2BY3 Middle third of oesophagus –– XA9CB6 Lower third of oesophagus –– XA0N03 Cervical oesophagus –– XA8JT3 Thoracic oesophagus –– XA0TN5 Abdominal oesophagus –– XA4YW8 Overlapping sites of oesophagus – XA28R6 Upper gastrointestinal tract, not elsewhere classified Has manifestation - multiple selections are allowed [select] MG30.10 Chronic cancer pain Has severity - only one may be selected [select] XS1G Stage I XS4P Stage II XS6H Stage III XS9R Stage IV Has alternative severity2 - only one may be selected [select] XS0J A Remission / Free of disease XS05 B Local Disease – XS0E Local limited – XS67 Locally advanced XS9S C Regional disease XS4Z D Distant disease
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