8A43.1 Neuromyelitis optica aquaporin-4 antibody negative

International Classification of Diseases for Mortality and Morbidity Statistics, 11th Revision, v2024-01

Neuromyelitis optica (NMO) is an inflammatory demyelinating disease of the central nervous system characterised mainly by attacks of uni- or bilateral optic neuritis (ON) and acute longitudinally extensive (> 3 vertebral segments) myelitis. This form is seronegative for aquaporin-4 antibodies. Some patients may be myelin oligodendrocyte glycoprotein (MOG) antibody positive.

synonyms

• Neuromyelitis optica aquaporin-4 antibody negative
• AQP-4 negative optical neuromyelitis

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