66736-0
LOINC Code
| LOINC code | 66736-0 | |
|---|---|---|
| name | ||
| description | The Silica Clotting Time (SCT) refers to a version of the activated partial thromboplastin time (aPTT) in which: 1) silica replace kaolin as activator in order to make the test amenable to automation (since kaolin is opaque) and 2) there is a screening reagent with very low phospholipid concentration, diminished compared to the standard aPTT reagent, to maximize sensitivity to lupus anticoagulant (LAC) and 3) there is a confirmatory reagent which uses excess phospholipid in an attempt to neutralize the putative LAC. (Original reference: Chantarangkul et al., Silica Clotting Time (SCT) as a Screening and Confirmatory Test Detection of the Lupus Anticoagulants. 1992. Thrombosis Research 67:355-365.) The normalize SCT ratio is calculated as follows: (Patient Screen Result in seconds / Mean Normal Screen Result in seconds) / (Patient Confirm Result in seconds / Mean Normal Confirm Result in seconds). The prototype test described by this code is the HemosIL(TM) Silica CLotting Time test. LabCorp performs a test similar to the screening step called "Partial Thromboplastin Time (PTT), Lupus Anticoagulant" (LabCorp #117002) which also uses silica and diminished PL, but apparently they do not report it as a normalized ratio. | |
| status | ACTIVE | |
Fully-Specified Name | ||
| component | Normalized silica clotting time | |
| property | Ratio | |
| time | Pt = Point in time: To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements. | |
| system | PPP = Platelet poor plasma | |
| scale | Qn = Quantitative: The result of the test is a numeric value that relates to a continuous numeric scale. Reported either as an integer, a ratio, a real number, or a range. The test result value may optionally contain a relational operator from the set {<=, <, >, >=}. Valid values for a quantitative test are of the form "7", "-7", "7.4", "-7.4", "7.8912", "0.125", "<10", "<10.15", ">12000", 1-10, 1:256 | |
| method | ||
Additional Names | ||
| short name | Clot; Clot tm; Clottable; COAGULATION; Coagulation time; Hematology; Heme; Normalized SCT; Plas; Platelet poor plasma; Point in time; QNT; Quan; Quant; Quantitative; Random; Rate; Ratios; R-time; Rto; SCT; Silicon dioxide | |
Basic Attributes | ||
| class | COAG | |
| type | 1 Laboratory | |
| order vs. observation | Normalized SCT | |
History/Usage | ||
| first released | ||
| last updated | 2.73 | |
| last change type | MIN - change to field other than name | |
Related Names | ||
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