IgG.intrathecally synthesized/IgG.total in Cerebral spinal fluid   68974-5

LOINC Code


LOINC code68974-5
nameIgG.intrathecally synthesized/IgG.total in Cerebral spinal fluid
descriptionNote that both the numerator and denominator are concentration of the same protein in the CSF, ..BUT the denominator is the total CSF concentration and the numerator is the contribution of the protein in the CSF that is MADE IN THE CSF (i.e. "intrathecally") ---as opposed to protein that has diffused in from the blood. The calculation is IgX(Intracthecal fraction) = [IgX(Intrathecally synthsized concentration)/IgX(Total CSF Concentration)]*100 from "Multiple Sclerosis (1998) 4, 111 - 117" From the same paper, the "IgX(Intrathecally synthsized concentration)" is complex to determine, but is based on the amount of protein in the CSF over and above that of the normal upper limit expected in the CSF (compared to that in blood). That 'over and above' amount is what is deemed to be produced in the CSF, which is the "Intrathecal Fraction"...... Same theme repeats in other papers (e.g. Am. J. Trop. Med. Hyg., 82(6), 2010, pp. 1094-1098)
statusACTIVE

Fully-Specified Name

componentIgG.intrathecally synthesized/IgG.total
propertyMFr  =  Mass Fraction
timePt  =  Point in time:  To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements.
systemCSF  =  Cerebral spinal fluid
scaleQn  =  Quantitative:  The result of the test is a numeric value that relates to a continuous numeric scale. Reported either as an integer, a ratio, a real number, or a range. The test result value may optionally contain a relational operator from the set {<=, <, >, >=}. Valid values for a quantitative test are of the form "7", "-7", "7.4", "-7.4", "7.8912", "0.125", "<10", "<10.15", ">12000", 1-10, 1:256
method

Additional Names

short nameIgG.IT/IgG.total MFr CSF

Basic Attributes

classCHEM
type1  Laboratory
order vs. observationObservation
formula (readable)IgG(Intracthecal fraction) = [IgG(Intrathecally synthsized concentration)/IgG(Total CSF Concentration)]*100
example UCUM units%
The Unified Code for Units of Measure (UCUM) is a code system intended to include all units of measures being contemporarily used in international science, engineering, and business (www.unitsofmeasure.org)
example unit%

Associated Observations

LOINC codes that represent optional associated observation(s) for a clinical observation or laboratory test. A LOINC term may represent a single associated observation or panel containing several associated observations.

History/Usage

first released
last updated2.70
last change typeMIN  - change to field other than name

Related Names

Cerebral spinal fluid
Cerebrospinal Fl
Chemistry
IgG intrathecally produced
IgG.intrathecal
IgG.IT
Immune globulin G
Immunoglobulin G
Mass fraction
Percent
Point in time
QNT
Quan
Quant
Quantitative
Random
Spinal Fl
Spinal Fld
Spinal Flu
Spinal Fluid
Tot
Totl

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.

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