Mycobacterium tuberculosis stimulated gamma interferon ESAT-6 Ag spot count [#] in Blood   74278-3

LOINC Code


LOINC code74278-3
nameMycobacterium tuberculosis stimulated gamma interferon ESAT-6 Ag spot count [#] in Blood
descriptionThe count of spots (0 to >20) in a patient's T cells that represent IFN-γ released in response to the presence of M. tuberculosis early secretory antigenic target-6 (ESAT-6) antigens. The spot count provides a measurement of the abundance of Mycobacterium tuberculosis sensitive effector T cells in the peripheral blood. This term is based on, but not limited in use to, Oxford Immunotec's T-SPOT.TB assay, used to diagnose M. tuberculosis. T-SPOT.TB assay uses enzyme-linked immunospot (ELISPOT) methodology to enumerate M. tuberculosis-sensitized T cells by capturing interferon-gamma (IFN-y) in the vicinity of T cells in the patient's whole blood. In the T-SPOT.TB assay, the test result is positive if [ESAT-6 (Panel A) - negative control spots] and/or [CFP10 (Panel B) - negative control spots] is greater than or equal to 8 spots. The test result is negative if both [Panel A - negative control] and/or [Panel B - negative control] is less than or equal to 4 spots.
statusACTIVE

Fully-Specified Name

componentMycobacterium tuberculosis stimulated gamma interferon.ESAT-6 Ag spot count
propertyNum  =  Number
timePt  =  Point in time:  To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements.
systemBld  =  Whole blood
scaleQn  =  Quantitative:  The result of the test is a numeric value that relates to a continuous numeric scale. Reported either as an integer, a ratio, a real number, or a range. The test result value may optionally contain a relational operator from the set {<=, <, >, >=}. Valid values for a quantitative test are of the form "7", "-7", "7.4", "-7.4", "7.8912", "0.125", "<10", "<10.15", ">12000", 1-10, 1:256
method

Additional Names

short nameM TB IFN-g.ESAT-6 Ag Bld

Basic Attributes

classMICRO
type1  Laboratory
order vs. observationBoth
example UCUM units{#}
The Unified Code for Units of Measure (UCUM) is a code system intended to include all units of measures being contemporarily used in international science, engineering, and business (www.unitsofmeasure.org)
example unit#

Associated Observations

LOINC codes that represent optional associated observation(s) for a clinical observation or laboratory test. A LOINC term may represent a single associated observation or panel containing several associated observations.

Member of these Panels

74281-7Mycobacterium tuberculosis stimulated gamma interferon and spot count panel - Blood

History/Usage

first released
last updated2.64
last change typeMIN  - change to field other than name

Related Names

Acid Fast
Acid Fast Bacilli
Acid fast bacillus
AFB
Blood
Cnt
Count
ID
IFN
IGRA
Infectious Disease
InfectiousDisease
Lung
M tb
M TB IFN-g
M TB IFN-g.ESAT-6 Ag
M tuberculosis
Microbiology
Mtb
Myco
Mycobact
Mycobacterium tuberculosum
Number
Point in time
Pulmonary
Pulmonology
QNT
Quan
Quant
Quantitative
Random
Respiratory
TB
Tuberculosis
WB
Whole blood

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.

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