Human papilloma virus 18+45 E6+E7 mRNA [Presence] in Cervix by NAA with probe detection   75694-0

LOINC Code


LOINC code75694-0
nameHuman papilloma virus 18+45 E6+E7 mRNA [Presence] in Cervix by NAA with probe detection
descriptionDetects E6/E7 viral messenger RNA (mRNA) of human papillomavirus (HPV) types 18 and 45 in cervical specimens from women with positive HPV assay results. E6/E7 oncogenes must be expressed for malignant transformation. For women 21-years and older with atypical squamous cells of undetermined significance (ASC-US) cervical cytology results, and HPV positive assay results, this assay can be used to assess the presence or absence of high-risk HPV genotypes 18, and/or 45. For women 30-years and older, the HPV 18, and/or 45 genotype assay can be used to test samples from women with HPV assay positive results, along with cervical cytology results. This assay has not been evaluated for HPV vaccinated patients or in cases of suspected abuse. It does not differentiate HPV 18 and HPV 45. This term was created for, but not limited in use to, the Aptima HPV 16 18/45 genotype assay which uses target capture, target amplification by transcription-mediated amplification and detection of the amplification products by hybridization protection. To report results for HPV 16 see Human papilloma virus 16 E6+E7 mRNA [Presence] in Cervix by Probe and signal amplification method [LOINC: 82456-5].
statusACTIVE

Fully-Specified Name

componentHuman papilloma virus 18+45 E6+E7 mRNA
propertyPrThr  =  Present or threshold:  The Property PrThr stands for “Presence or Threshold”, meaning either a) the actual presence or absence of an analyte, or b) that the amount of analyte detected is over some predetermined threshold.
timePt  =  Point in time:  To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements.
systemCvx  =  Cervix
scaleOrd  =  Ordinal:  Ordered categorical responses, e.g., 1+, 2+, 3+; positive, negative; reactive, indeterminate, nonreactive.
methodProbe.amp.tar

Additional Names

short nameHPV18+45 E6+E7 mRNA Cvx Ql NAA+probe

Basic Attributes

classMICRO
type1  Laboratory
order vs. observationBoth

Associated Observations

LOINC codes that represent optional associated observation(s) for a clinical observation or laboratory test. A LOINC term may represent a single associated observation or panel containing several associated observations.

Member of these Panels

90988-7HEDIS 2019-2020 Value Set - HPV Tests
90988-7HEDIS 2019-2020 Value Set - HPV Tests
82457-3Human papilloma virus 16 and 18+45 E6+E7 mRNA panel - Cervix by NAA with probe detection

History/Usage

test rank3814 of 2000 most commonly performed tests by labs in USA
first released
last updated2.73
last change typeMIN  - change to field other than name
change reasonThe PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016. Changed the method from 'Probe.amp.sig' to 'Probe.amp.tar' to correctly reflex the HPA procedure.

Related Names

3 Self-Sustaining Sequence Replication
3SR SR
Amplif
Amplification
Amplified
Cervix
DNA NUCLEIC ACID PROBE
DNA probe
Genital tract
Genital warts
Gyn
Gynecology
HPV
HPV 18
HPV 45
HPV18
HPV18+45 E6+E7 mRNA
Human papilloma virus
Human papillomavirus
ID
Infectious Disease
InfectiousDisease
LAT
LCR
Ligase chain reaction
Ligation-activated transcription
Microbiology
NAA+probe
NAAT
NASBA
Nucleic acid sequence based analysis
OB
ObGyn
Obstetrics
Ordinal
Papilloma virus high risk
PCR
Point in time
Polymerase chain reaction
PR
Probe amp
Probe with ampification
Probe with target amplification
QBR
QL
Qual
Qualitative
Random
Screen
SDA
Strand Displacement Amplification
TMA
Transcription mediated amplification

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.

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