Breast cancer 10-year risk of distant recurrence score Calculated by Prosigna   76544-6

LOINC Code


LOINC code76544-6
nameBreast cancer 10-year risk of distant recurrence score Calculated by Prosigna
descriptionThe 10-year breast cancer distant recurrence risk score (also referred to as ROR Score or Risk of Recurrence Score) is a numerical score on a scale of 0 -100 that is calculated using a statistical model that includes: 1) the results from a 50-gene expression assay performed on formalin fixed paraffin embedded breast tumor tissue previously diagnosed as invasive carcinoma; 2) proliferation score; and 3) gross tumor size. The calculated score and information about lymph node status are used together to classify the patient into a risk category for distant breast cancer recurrence at 10 years. This term was created for the Prosigna™ Breast Cancer Prognostic Gene Signature assay, which is intended for use in postmenopausal women with node-negative (Stage I or II) or node-positive (Stage II), hormone receptor-positive (HR+) breast cancer who have undergone surgery and are to be treated with adjuvant endocrine therapy alone.
statusACTIVE

Fully-Specified Name

componentBreast cancer 10Y risk of distant recurrence score
propertyScore
timePt  =  Point in time:  To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements.
system^Patient
scaleQn  =  Quantitative:  The result of the test is a numeric value that relates to a continuous numeric scale. Reported either as an integer, a ratio, a real number, or a range. The test result value may optionally contain a relational operator from the set {<=, <, >, >=}. Valid values for a quantitative test are of the form "7", "-7", "7.4", "-7.4", "7.8912", "0.125", "<10", "<10.15", ">12000", 1-10, 1:256
methodCalculated.Prosigna

Additional Names

short nameBrst ca 10Y dist recur score Prosigna

Basic Attributes

classMOLPATH
type1  Laboratory
order vs. observationBoth
formula (readable)Calculated using a Cox model that includes coefficients for the gene expression assay results, proliferation score, and gross tumor size.
example UCUM units{score}
The Unified Code for Units of Measure (UCUM) is a code system intended to include all units of measures being contemporarily used in international science, engineering, and business (www.unitsofmeasure.org)
example unitscore

Associated Observations

LOINC codes that represent optional associated observation(s) for a clinical observation or laboratory test. A LOINC term may represent a single associated observation or panel containing several associated observations.

Member of these Panels

76546-1Breast cancer 10-year risk of distant recurrence panel by Prosigna

History/Usage

test rank17578 of 2000 most commonly performed tests by labs in USA
first released
last updated2.73
last change typeMIN  - change to field other than name
change reasonOrder_Obs: changed from 'observation' to 'both' to reflect that the LOINC code can also be used as an order code.

Related Names

breast cancer
Brst ca 10Y risk dist recur score
Calc
Calc.Prosigna
Calculation
Molecular pathology
MOLPATH
PAM50
Point in time
Prosigna
Psoriasis Care Satisfaction questionnaire
QNT
Quan
Quant
Quantitative
Random
Risk of recurrence score
ROR
Scale

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.

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