SAP and XIAP [Interpretation] in Leukocytes by Flow cytometry (FC)   82937-4

LOINC Code


LOINC code82937-4
nameSAP and XIAP [Interpretation] in Leukocytes by Flow cytometry (FC)
descriptionAnalysis of SLAM (signaling lymphocytic activation molecule)-associated protein (SAP) and X-linked inhibitor of apoptosis protein (XIAP) levels by flow cytometry is performed as a preliminary screen for X-linked lymphoproliferative (XLP) disease and X-linked familial hemophagocytic lymphohistiocytosis (HLH). If SAP protein levels are absent or decreased, XLP is suspected. If XIAP protein levels are absent or decreased, HLH (aka XLP-2) is suspected. The diagnosis is confirmed by genetic analysis of the associated genes (SH2D1A gene for XLP, BIRC4 gene for HLH).
statusACTIVE

Fully-Specified Name

componentSignaling lymphocytic activation molecule (SLAM)-associated & X-linked inhibitor of apoptosis protein
propertyImp  =  Impression/interpretation of study
timePt  =  Point in time:  To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements.
systemWBC  =  Leukocytes
scaleNom  =  Nominal:  Nominal or categorical responses that do not have a natural ordering. (e.g., names of bacteria, reported as answers, categories of appearance that do not have a natural ordering, such as, yellow, clear, bloody.
methodFlow cytometry

Additional Names

short nameSAP + XIAP WBC FC-Imp

Basic Attributes

classCHEM
type1  Laboratory
order vs. observationBoth

Associated Observations

LOINC codes that represent optional associated observation(s) for a clinical observation or laboratory test. A LOINC term may represent a single associated observation or panel containing several associated observations.

History/Usage

first released
last updated2.58
last change typeADD  - added

Related Names

(SLAM)-associated protein
Assoc
BIRC4
Chemistry
Duncan disease
Dynamic
Esoteric
FC
Hemophagocytic Lymphohistiocytosis
HLH
Impression
Impression/interpretation of study
Impressions
Inhib
Inhibit
Interp
Interpretation
Leukocytes
Nominal
Point in time
PR
Prot
Purtilo syndrome
Random
SAP
SAP + XIAP
WBCs
White blood cells
XIAP
X-Linked Lymphoproliferative Disorder
XLP
XLP1
XLP2

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.

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