Borrelia afzelii+burgdorferi+garinii IgG band pattern [Interpretation] in Serum by Line blot 87276-2
LOINC Code
| LOINC code | 87276-2 | ||
|---|---|---|---|
| name | Borrelia afzelii+burgdorferi+garinii IgG band pattern [Interpretation] in Serum by Line blot | ||
| description | The pattern of reactive bands specific to IgG antibodies associated with Borrelia afzelii, B burgdorferi, and B garinii species in human serum. Antibodies against p83, p58, p43, p39, p30, OspC, p21, Osp17/DbpA, p14 and VlsE antigens are characterized as highly specific for Borrelia species. The presence of specific bands suggests a recent infection of Lyme disease.This term was created for, but not limited in use to, the Borrelia ViraStripe IgG assay, which uses native, purified antigens immobilized on a test strip to which patient antibodies, if present, will bind. Various manufacturers label this method as an immunoblot technique. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the laboratory assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method is Line blot. | ||
| status | ACTIVE | ||
Fully-Specified Name | |||
| component | Borrelia afzelii+burgdorferi+garinii Ab.IgG band pattern | ||
| property | Imp = Impression/interpretation of study | ||
| time | Pt = Point in time: To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements. | ||
| system | Ser = Serum | ||
| scale | Nom = Nominal: Nominal or categorical responses that do not have a natural ordering. (e.g., names of bacteria, reported as answers, categories of appearance that do not have a natural ordering, such as, yellow, clear, bloody. | ||
| method | Line blot = Line blot: A membrane strip pre-coated with a specific set of antigens in parallel lines that are incubated with antibodies in order to detect the targets of interest. | ||
Additional Names | |||
| short name | B afz+burg+gari IgG Ptrn Ser Ln blot | ||
Basic Attributes | |||
| class | MICRO | ||
| type | 1 Laboratory | ||
| order vs. observation | Observation | ||
Associated Observations | |||
LOINC codes that represent optional associated observation(s) for a clinical observation or laboratory test. A LOINC term may represent a single associated observation or panel containing several associated observations. | |||
Member of these Panels | |||
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History/Usage | |||
| first released | |||
| last updated | 2.67 | ||
| last change type | MIN - change to field other than name | ||
| change reason | This term was created for an assay that uses a membrane strip pre-coated with a specific set of antigens in parallel lines. Because the antigens are seperated by electrophoresis/chromatographic separation during manufacturing, not during the test procedure itself, this test was assigned a LOINC Method of Immunoassay (IA) and not Immunoblot (IB). However, upon further review of IA, IB, and Immunoblot strip methodologies and regulatory distinctions between these, we changed the Method from IA to Line blot so that users can distinguish between these three Methods. The meaning of the term has not changed since it was created for an IB strip assay as described in the term description. | ||
Related Names | |||
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