PNH GPI-Linked WBC and RBC Ag Panel - Blood   90735-2

LOINC Code


LOINC code90735-2
namePNH GPI-Linked WBC and RBC Ag Panel - Blood
descriptionThe tests in this panel detect glycosylphosphatidylinositol (GPI)-linked proteins including CD14 for monocytes, CD16 and 24 for granulocytes, and CD59 for erythrocytes. In addition, fluorescent aerolysin (FLAER) which selectively binds to GPI anchor proteins, is also used to detect the presence or absence of those anchors. Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired hematologic disorder of erythroid, granulocytic, and megakaryocytic cell lines. The abnormal cells in PNH are missing the GPI-linked proteins due to mutations in the phosphatidylinositol glycan A gene (PIGA).
statusACTIVE

Fully-Specified Name

componentParoxysmal nocturnal hemoglobinuria GPI-Linked WBC & RBC Ag Panel
property-
timePt  =  Point in time:  To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements.
systemBld  =  Whole blood
scale-
method

Additional Names

short namePNH GPI-Lkd WBC + RBC Ag Pnl Bld

Basic Attributes

classPANEL.CELLMARK
type1  Laboratory
order vs. observationOrder

Panel Components

33662-8Erythrocytes.CD59 deficient/100 erythrocytes in Blood
90738-6Erythrocytes.CD59 complete loss/100 erythrocytes in Blood
90737-8CD24-FLAER- cells/100 cells.CD15 (Neutrophils) in Blood
90736-0CD14-FLAER- cells/100 cells.CD33 (Monocytes) in Blood

Associated Observations

LOINC codes that represent optional associated observation(s) for a clinical observation or laboratory test. A LOINC term may represent a single associated observation or panel containing several associated observations.

History/Usage

first released
last updated2.65
last change typeADD  - added

Related Names

Blood
CELL MARKERS
Glycosylphosphatidylinositol-linked proteins
Pan
PANEL.CELLMARK
Panl
Paroxysmal nocturnal hemoglobinuria
PLINK
PNH
PNH GPI-Linked WBC + RBC
PNH GPI-Lkd WBC + RBC Ag
PNH GPI-Lkd WBC + RBC Ag Pnl
Pnl
Point in time
Random
WB
Whole blood

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.

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