Code Change for Provenge Administration

On July 1, 2011, a new code for Provenge administration was created. HCPCS code Q2043 , Sipuleucel-T, minimum of 50 million autologous cd54+ cells activated with PAP-GM-CSF, including leukapheresis and all other preparatory procedures, per infusion , was created and replaced HCPCS code C9273 , Sipuleucel-T, minimum of 50 million autologous CD54+ cells activated with PAP-GM-CSF, including leukapheresis and all other preparatory procedures, per infusion , for this service.  HCPCS code C9273 was effective October 1, 2010 and deleted on June 30 2011. The reporting of HCPCS code Q2043 includes the drug administered, all preparatory procedures for the administration of the drug...

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Note:  The following article synopsis was NOT provided by the AHA. It was created by Find-A-Code/innoviHealth.

Article Overview

This premium article covers a HCPCS code change affecting Provenge administration, including the timing of the update, the replacement of an earlier code, and the general scope of what the reported service encompasses. It is intended for coders and billing professionals who need to understand the applicable HCPCS and CPT reporting context for this treatment administration.

Why This Topic Matters

Updates like this affect claim reporting, code selection, and date-specific billing accuracy for specialty infusion services. Understanding the change helps prevent use of outdated codes and supports correct alignment between HCPCS reporting and the separately billed procedural component.

Article Sections

  1. Code Change for Provenge Administration

    Overview of the code update and the billing context for the service. The section discusses timing, replacement of an earlier code, and the relationship between the administration workflow and related procedure reporting.

What You Will Learn

  • The timing and scope of a HCPCS code update for a specialty drug administration service.
  • How an earlier code was superseded by a later code for the same general service.
  • Which parts of the treatment workflow are discussed as part of the reported service.
  • How the article frames the separation between HCPCS reporting and the associated procedural claim component.

Who Should Read This

  • Medical coders
  • Billing specialists
  • Revenue cycle staff
  • Oncology practice administrators
  • Compliance staff

Codes Discussed


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