AHA Coding Clinic® for HCPCS - 2025 Issue 1; For Your Information

New CPT Proprietary Laboratory Analyses (PLA) codes effective April 1, 2025

New CPT PLA codesCPT code Long descriptor Effective date 0529U Hematology (venous thromboembolism [VTE]), genome-wide single nucleotide polymorphism variants, including F2 and F5 gene analysis, and Leiden variant, by microarray analysis, saliva, report as risk score for VTE April 1, 2025 0530U Oncology (pan-solid tumor), ctDNA, utilizing plasma, next-generation sequencing (NGS) of 77 genes, 8 fusions, microsatellite instability, and tumor mutation burden, interpretative report for single-nucleotide variants, copy-number alterations, with therapy association April 1, 2025 0531U Infectious disease (acid-fast bacteria and invasive fungi), DNA (673 organisms), next-generation sequencing, plasma April 1, 2025 0532U Rare diseases (constitutional disease/hereditary disorders), rapid...

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