AHA Coding Clinic® for HCPCS - 2023 Quarter 4; For Your Information
New, Deleted and Revised CPT Proprietary Laboratory Analyses (PLA) Codes
New, deleted and revised CPT Proprietary Laboratory Analyses (PLA) codes effective October 1, 2023 New CPT PLA Codes CPT Code Long Descriptor Effective Date 0402U Infectious agent (sexually transmitted infection), Chlamydia trachomatis, Neisseria gonorrhoeae, Trichomonas vaginalis, Mycoplasma genitalium, multiplex amplified probe technique, vaginal, endocervical, or male urine, each pathogen reported as detected or not detected October 1, 2023 0403U Oncology (prostate), mRNA, gene expression profiling of 18 genes, first-catch post-digital rectal examination urine (or processed first-catch urine), algorithm reported as percentage of likelihood of detecting clinically significant prostate cancer October 1, 2023 0404U Oncology (breast), semiquantitative measurement of thymidine...
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Article Overview
This article covers a CPT PLA code update effective October 1, 2023. It is useful for coding professionals, laboratory billers, compliance teams, and revenue cycle staff who need to track PLA code changes across specialties such as oncology, infectious disease, hematology, nephrology, psychiatry, neurology-related testing, cardiovascular disease, gastroenterology, and rare disease genetics. The article presents newly established PLA codes, deleted PLA codes, and revised PLA code descriptors so readers can understand the scope of the quarterly update and determine whether any lab test documentation or code crosswalks may be affected.
Why This Topic Matters
PLA code updates can affect claim accuracy, code maintenance, and internal charge capture workflows. Reviewing these changes helps organizations keep laboratory coding references current when managing molecular, genomic, immunoassay, and other specialized diagnostic services.
Article Sections
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New CPT PLA Codes
Lists newly effective PLA entries across multiple clinical areas and laboratory methodologies. The section is organized by code and effective date.
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Deleted CPT PLA Codes
Identifies PLA entries that are no longer effective as of the stated date. The section supports code maintenance and historical reference tracking.
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Revised CPT PLA Codes
Shows PLA entries with updated descriptors effective on the stated date. The section highlights changes in code text for selected laboratory tests.
What You Will Learn
- How the article is organized around new, deleted, and revised CPT PLA updates.
- Which specialties and test categories are represented in the PLA update.
- What types of laboratory coding changes were made in the October 2023 update.
- How to recognize whether a PLA code set change may affect laboratory reference materials or billing workflows.
Who Should Read This
- Medical coders
- Laboratory billing staff
- Compliance teams
- Revenue cycle staff
- Pathology and laboratory managers
- Healthcare documentation specialists
Codes Discussed
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