New, Deleted, and Revised CPT Proprietary Laboratory Analyses (PLA) codes Effective October 1, 2026

Newly released changes to the CPT Proprietary Laboratory Analyses codes consist of the addition of 39 codes, deletion of 3 codes, and the revision of 3 codes. New CPT PLA Codes CPT Code Long Descriptor Effective Date 0660U Human papillomavirus (HPV), genotypes 18, 31, 33, and 35, cell-free DNA (cfDNA), whole blood, multiplex digital droplet PCR (ddPCR), quantitative October 1, 2026 0661U Human papillomavirus (HPV), genotype 16, cell-free DNA (cfDNA), whole blood, digital droplet PCR (ddPCR), quantitative October 1, 2026 0662U Transplantation medicine (kidney allograft rejection), mRNA, gene-expression profiling by real-time quantitative PCR of 12 genes (11 content and...

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