New proprietary laboratory analyses (PLA) codes

New Proprietary Laboratory Analyses (PLA) codes effective July 1, 2022 CPT Code Long Descriptor Effective Date 0323U Infectious agent detection by nucleic acid (DNA and RNA), central nervous system pathogen, metagenomic next-generation sequencing, cerebrospinal fluid (CSF), identification of pathogenic bacteria, viruses, parasites, or fungi July 1, 2022 0324U Oncology (ovarian), spheroid cell culture, 4-drug panel (carboplatin, doxorubicin, gemcitabine, paclitaxel), tumor chemotherapy response prediction for each drug July 1, 2022 0325U Oncology (ovarian), spheroid cell culture, poly (ADPribose) polymerase (PARP) inhibitors (niraparib, olaparib, rucaparib, velparib), tumor response prediction for each drug July 1, 2022 0326U Targeted genomic sequence analysis panel...

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Note:  The following article synopsis was NOT provided by the AHA. It was created by Find-A-Code/innoviHealth.

Article Overview

This page covers newly effective CPT Proprietary Laboratory Analyses (PLA) codes taking effect on July 1, 2022. It is relevant to laboratory billing, pathology, oncology, infectious disease, and molecular diagnostics stakeholders who need to track newly added test identifiers and understand the broad testing categories represented. The article presents the code list and the general clinical and technical themes associated with these PLA updates.

Why This Topic Matters

PLA code updates can affect charge capture, claim submission, and tracking of emerging laboratory tests. Readers use this type of update to stay current with newly available CPT laboratory identifiers and the broad diagnostic areas they represent.

What You Will Learn

  • Which new PLA codes became effective on July 1, 2022
  • What broad laboratory and molecular testing categories are represented
  • How the article organizes the updated CPT PLA code list
  • Which specialties and diagnostic areas are associated with the new codes

Who Should Read This

  • Medical coders
  • Billers
  • Laboratory staff
  • Pathology practices
  • Oncology billing teams
  • Molecular diagnostics professionals
  • Compliance staff

Codes Discussed


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