AHA Coding Clinic® for ICD-10-CM and ICD-10-PCS - 2021 Issue 4; ICD-10-CM New/Revised Codes

Anemia Due to Pyruvate Kinase Deficiency Anemia Due to Other Disorders of Glycolytic Enzymes

New codes have been created to describe anemia due to pyruvate kinase deficiency and anemia due to other disorders of glycolytic enzymes as follows:D55.21 Anemia due to pyruvate kinase deficiency D55.29 Anemia due to other disorders of glycolytic enzymes Red blood cell (RBC) pyruvate kinase (PK) deficiency is a rare congenital hemolytic anemia caused by mutations in the pyruvate kinase liver and red blood cells (PKLR) gene that encodes PK. The PKLR gene provides instructions for making an enzyme called PK. The PK enzyme is involved in a critical energy-producing process known as glycolysis. PK deficiency is...

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