AHA Coding Clinic® for ICD-9 - 2010 Issue 2; Ask the Editor

Chemotherapy and Dihydropyrimidine Dehydrogenase Deficiency (DPD)

A patient with colon cancer status post resection was admitted with relentless chemo-induced diarrhea following a recent course of 5-fluorouracil (5-FU) chemotherapy. The patient was found to be deficient in an enzyme which metabolizes 5-FU, and the provider diagnosed dihydropyrimidine dehydrogenase (DPD) deficiency. What is the appropriate code assignment for DPD deficiency? ...

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