AHA Coding Clinic® for ICD-9 - 2013 Issue 4; Ask the Editor

Methylenetetrahydrofolate Reductase Heterozygosity/Deficiency and PAI-1 Polymorphism

The patient has been diagnosed with methylenetetrahydrofolate reductase (MTHFR) heterozygosity and PAI-1 polymorphism. The provider documented, “aspirin prescribed for MTHFR mutation.” After researching the subject, it is unclear if heterozygosity is the same as MTHFR deficiency. Is code 270.4 assigned for the MTHFR heterozygosity? Additionally, what is the code assignment for PAI-1 polymorphism? ...

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