AHA Coding Clinic® for ICD-9 - 2008 Issue 4; VOLUMES 1 AND 2 NEW/REVISED CODES

Post-Transplant Lymphoproliferative Disorder

Effective October 1, 2008 code 238.77, Post-transplant lymphoproliferative disorder (PTLD), has been created for this condition that occurs when a group of B-cells grow out of control following solid organ/bone marrow transplant in patients with weakened immune systems. While an estimated 87% of PTLD cases are of B-cell origin, there are reports of T-cell and null cell origin. PTLD is most often associated with the primary or reactivation of latent Epstein-Barr virus (EBV) infection. Prevalence is related to the transplanted organ with a higher incidence in intestinal and heart transplant; and the immunosuppressant medication. PTLD may present with...

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