AHA Coding Clinic® for ICD-10-CM and ICD-10-PCS - 2025 Quarter 4; ICD-10-PCS New/Revised Codes Section X—New Technology
Ultrasound Ablation of Brain
A patient with recurrent multifocal glioblastoma was admitted for tumor destruction via focused ultrasound sonodynamic therapy. Several hours prior to the procedure, the patient was infused peripherally with intravenous SONALA- 001 , (proprietary formulation of aminolevulinic acid) which crossed the blood brain barrier and accumulated in the glioblastoma cells. After absorption of the SONALA- 001 , the tumor cells became light sensitive. The tumor locations were confirmed in the left cerebral ventricle and frontal lobe. The tumors were then targeted, and the magnetic resonance guided focused ultrasound therapy was delivered to the photo sensitive tumor cells. The ultrasound in combination with the drug-induced sensitivity produced a burst of light, killing the tumor cells. What are the ICD-10-PCS codes for the SONALA- 001 infusion followed by tumor ablation via noninvasive MRI guided focused ultrasound sonodynamic therapy? ...
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Article Overview
This article covers ICD-10-PCS coding for brain tumor destruction using focused ultrasound therapy and related sonodynamic or photodynamic treatment context. It is aimed at coding professionals who need to understand the table changes, the technology setting, and the procedure scenario discussed in the article. The article also places the topic in the context of image-guided treatment and drug-associated tumor sensitivity, without serving as a full coding reference.
Why This Topic Matters
Focused ultrasound procedures for brain tumors are a specialized ICD-10-PCS topic, and this article helps readers recognize the relevant table structure and clinical context so they can evaluate whether the premium guidance applies to their case or audit question.
Article Sections
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ICD-10-PCS table updates for focused ultrasound
Introduces the affected ICD-10-PCS table and the body part, technology, and approach elements associated with this topic. It frames the coding change in broad terms without listing coding instructions.
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Clinical context and procedure description
Describes the treatment workflow using image guidance, drug infusion, and focused ultrasound in a brain tumor setting. The section provides clinical background for the coding discussion.
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Example case involving recurrent glioblastoma
Presents a sample scenario involving multifocal brain tumor treatment and focused ultrasound therapy. It gives context for the article’s coding question without reproducing detailed code-selection logic.
What You Will Learn
- How the article frames ICD-10-PCS coding for focused ultrasound treatment of brain tumors.
- What clinical context is used to illustrate tumor ablation in the brain.
- How image guidance and drug-associated tumor sensitivity are presented in the discussion.
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Who Should Read This
- ICD-10-PCS coders
- Medical coding auditors
- Health information management professionals
- Coding educators
Codes Discussed
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