CPT Knowledgebase - Nov 2, 2018

What is the correct code to report a human papillomavirus (HPV) high-risk (HR) assay that is a qualitative in situ hybridization (ISH) analysis intended for the use on formalin-fixed, paraffin-embedded (FFPE) tissue stained with an automated staining instrument? The HPV mRNA probes 16, 18, and 33 are combined into one dispenser vial to make a cocktail; one slide is stained; and an interpretation of a positive or negative result is reported.

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