EB13 Stevens-Johnson syndrome or toxic epidermal necrolysis
International Classification of Diseases for Mortality and Morbidity Statistics, 11th Revision, v2024-01
A spectrum of severe and life-threatening hypersensitivity disorders affecting skin and mucous membranes, most commonly precipitated by an idiosyncratic reaction to medication. Stevens-Johnson syndrome (SJS) always involves mucosal surfaces but the skin involvement is limited by definition to <10% body surface area (BSA). Toxic epidermal necrolysis (TEN) may sometimes spare mucous membranes but skin involvement is by definition >30% BSA. An intermediate form is recognised in which mucosal involvement is accompanied by skin involvement of 10-30% BSA (SJS-TEN overlap syndrome). All forms result in extensive sloughing and ulceration and carry a significant risk of fatal outcome.
code elsewhere
sections/codes in this section (EB13-EB13)
- Stevens-Johnson syndrome (EB13.0)
- Toxic epidermal necrolysis (EB13.1)
- Stevens-Johnson and toxic epidermal necrolysis overlap syndrome (EB13.2)
synonyms
- Stevens-Johnson syndrome or toxic epidermal necrolysis
- SJS/TEN - [Stevens-Johnson syndrome and toxic epidermal necrolysis]
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