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3A51.5 Haemoglobin C disease

International Classification of Diseases for Mortality and Morbidity Statistics, 11th Revision, v2024-01

A disease caused by the bi-parental gene that encodes for haemoglobin C. This disease is characterised by abnormal structure of one of the globin chains of the haemoglobin molecule. This disease may present with mild haemolytic anaemia, increased risk for gallstones, enlarged spleen, episodes of joint pain, and increased risk of infection. This disease is confirmed by identification of the haemoglobin C gene by genetic testing.

exclusions

• Hereditary persistence of fetal haemoglobin  (3A50.4)

synonyms

• Haemoglobin C disease
• Homozygous HbC carriers
• Homozygous (HbC/HbC, HbC/beta-thal and other)

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