Amyloid probability score in Plasma by Calculation   106939-2

LOINC Code


LOINC code106939-2
nameAmyloid probability score in Plasma by Calculation
descriptionThe term repersents The PrecivityAD2™ test. This test is an analytically and clinically validated blood test designed to assist healthcare providers in diagnosing Alzheimer's disease (AD) in patients with mild cognitive impairment or dementia. It quantifies specific plasma amyloid beta and tau peptides using liquid chromatography-tandem mass spectrometry (LC-MS/MS) to calculate the Aβ42/40 and p-tau217/np-tau217 ratios. These ratios are combined in a proprietary algorithm to produce the Amyloid Probability Score 2 (APS2), a numerical value from 0-100 that indicates the likelihood of brain amyloid plaques. By providing a non-invasive alternative to PET scans, the PrecivityAD2™ test enhances diagnostic accuracy while mitigating the effects of confounding factors.
statusACTIVE

Fully-Specified Name

componentAmyloid plaques probability score
propertyScore
timePt  =  Point in time:  To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements.
systemPlas  =  Plasma
scaleNom  =  Nominal:  Nominal or categorical responses that do not have a natural ordering. (e.g., names of bacteria, reported as answers, categories of appearance that do not have a natural ordering, such as, yellow, clear, bloody.
methodCalculation

Additional Names

short nameAmyloid prob score Plas Calc

Basic Attributes

classSERO
type1  Laboratory
order vs. observationBoth
formula (readable)The APS2 result is a composite score ranging from 0-100 that demonstrates the strongest correlation with brain amyloid pathology compared to the individual biomarkers (Aβ42/40 Ratio or p-tau217 Ratio) considered separately.
example UCUM units{score}
The Unified Code for Units of Measure (UCUM) is a code system intended to include all units of measures being contemporarily used in international science, engineering, and business (www.unitsofmeasure.org)
example unitScore

Associated Observations

LOINC codes that represent optional associated observation(s) for a clinical observation or laboratory test. A LOINC term may represent a single associated observation or panel containing several associated observations.

History/Usage

first released
last updated2.79
last change typeADD  - added

Related Names

Alzheimer disease
Alzheimer's disease
Amyloid plaques score
APS
Calc
Calcn
Calculated
Nominal
Pl
Plasma
Plsm
Point in time
Random
Scale
Serology

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.

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