IgG clearance/Albumin clearance [Ratio] in Serum and CSF   14117-6

LOINC Code


LOINC code14117-6
nameIgG clearance/Albumin clearance [Ratio] in Serum and CSF
descriptionRatio of a patient's IgG and albumin in CSF to the IgG and albumin in serum is of diagnostic value in a number of neurological disorders. Normally CSF albumin and IgG are derived from the serum, whereas in patients with active multiple sclerosis, the increased CSF IgG is believed to be synthesized within the CSF. The CSF Index is a calculated value which expresses the ratio of IgG to albumin in CSF, to the ratio of IgG to albumin in serum. An elevated ratio suggests local CNS synthesis of IgG. An increased CSF/IgG Index is found in diseases such as MS, neurosyphilis, subacute sclerosing panencephalitis (SSPE), chronic CNS infections and CNS lupus erythematosus.
statusACTIVE

Fully-Specified Name

componentIgG clearance/Albumin clearance
propertyRatio
timePt  =  Point in time:  To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements.
systemSer+CSF
    Ser  =  Serum
    CSF  =  Cerebral spinal fluid
scaleQn  =  Quantitative:  The result of the test is a numeric value that relates to a continuous numeric scale. Reported either as an integer, a ratio, a real number, or a range. The test result value may optionally contain a relational operator from the set {<=, <, >, >=}. Valid values for a quantitative test are of the form "7", "-7", "7.4", "-7.4", "7.8912", "0.125", "<10", "<10.15", ">12000", 1-10, 1:256
method

Additional Names

short nameIgG/Alb clear Ser+CSF-Rto

Basic Attributes

classCHEM
type1  Laboratory
order vs. observationObservation
formula (readable)IgG index = (IgG, CSF/IgG, serum)/(albumin, CSF/albumin,serum)

Associated Observations

LOINC codes that represent optional associated observation(s) for a clinical observation or laboratory test. A LOINC term may represent a single associated observation or panel containing several associated observations.

Member of these Panels

55121-8Multiple sclerosis panel - Serum and CSF

History/Usage

test rank2067 of 2000 most commonly performed tests by labs in USA
first released
last updated2.73
last change typeMIN  - change to field other than name

Related Names

Alb
Alb clear
Both serum and cerebrospinal fluid
Cerebral spinal fluid
Cerebrospinal Fl
Chemistry
Cl
Clear
Clearanc
Clearances
Clr
Immune globulin G
Immunoglobulin G
Point in time
Protein.albumin
QNT
Quan
Quant
Quantitative
Random
Ratios
Rto
Serum
Spinal Fl
Spinal Fld
Spinal Flu
Spinal Fluid
SR

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.

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