HLA-A+B+C SBT [Interpretation] by High resolution   53767-0

LOINC Code


LOINC code53767-0
nameHLA-A+B+C SBT [Interpretation] by High resolution
descriptionHLA-ABC sequence based typing results in HLA allele assignment for each HLA locus(A,B,C). HLA antigens are the major histocompatibility antigens. HLA Class 1 Sequence-Based typing (HLA-SBT) is used to identify HLA allelic polymorphisms at the level of individual nucleotides using genomic DNA amplified by polymerase chain reaction(PCR). If fewer than two alleles are reported for a locus, the patient can most likely be considered homozygous for that locus, but there is a possibility of an undetected rare allele. HLA-SBT should be used in addition to HLA Class 1 serology and/or low to intermediate resolution molecular typing using either SSP(sequence-specific primers) or SSOPH(sequence-specific oligonucleotide blot hydridization) technology. For clinical purposes, this test should be used as a reflex test to identify unrelated bone marrow donors who are HLA A,B, and C genotypic matches with the intended recipient.
statusACTIVE

Fully-Specified Name

componentHLA-A+B+C SBT
    B  =  Buccal
propertyImp  =  Impression/interpretation of study
timePt  =  Point in time:  To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements.
systemBld/Tiss
    Bld  =  Whole blood
    Tiss  =  Tissue, unspecified
scaleNom  =  Nominal:  Nominal or categorical responses that do not have a natural ordering. (e.g., names of bacteria, reported as answers, categories of appearance that do not have a natural ordering, such as, yellow, clear, bloody.
methodHigh resolution

Additional Names

short nameHLA-A+B+C SBT High Res-Imp

Basic Attributes

classHLA
type1  Laboratory
order vs. observationObservation

Associated Observations

LOINC codes that represent optional associated observation(s) for a clinical observation or laboratory test. A LOINC term may represent a single associated observation or panel containing several associated observations.

History/Usage

test rank4653 of 2000 most commonly performed tests by labs in USA
first released
last updated2.73
last change typeMIN  - change to field other than name
change reasonThis test is commonly performed on cells found in saliva and buccal swabs as well as blood specimens. Changed specimen from 'Bld' to 'Bld/Tiss' to represent both specimen types.

Related Names

A,B
Blood
Genetics
Heredity
Heritable
HLA ANTIGEN
HLA class I
Human Leukocyte Antigen
Impression
Impression/interpretation of study
Impressions
Inherited
Interp
Interpretation
Nominal
Point in time
Random
Sequence based typing
Tissue
Tissue, unspecified
WB
Whole blood
Whole blood or Tissue

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.

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