Normalized silica clotting time of Platelet poor plasma   66736-0

LOINC Code


LOINC code66736-0
nameNormalized silica clotting time of Platelet poor plasma
descriptionThe Silica Clotting Time (SCT) refers to a version of the activated partial thromboplastin time (aPTT) in which: 1) silica replace kaolin as activator in order to make the test amenable to automation (since kaolin is opaque) and 2) there is a screening reagent with very low phospholipid concentration, diminished compared to the standard aPTT reagent, to maximize sensitivity to lupus anticoagulant (LAC) and 3) there is a confirmatory reagent which uses excess phospholipid in an attempt to neutralize the putative LAC. (Original reference: Chantarangkul et al., Silica Clotting Time (SCT) as a Screening and Confirmatory Test Detection of the Lupus Anticoagulants. 1992. Thrombosis Research 67:355-365.) The normalize SCT ratio is calculated as follows: (Patient Screen Result in seconds / Mean Normal Screen Result in seconds) / (Patient Confirm Result in seconds / Mean Normal Confirm Result in seconds). The prototype test described by this code is the HemosIL(TM) Silica CLotting Time test. LabCorp performs a test similar to the screening step called "Partial Thromboplastin Time (PTT), Lupus Anticoagulant" (LabCorp #117002) which also uses silica and diminished PL, but apparently they do not report it as a normalized ratio.
statusACTIVE

Fully-Specified Name

componentNormalized silica clotting time
propertyRatio
timePt  =  Point in time:  To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements.
systemPPP  =  Platelet poor plasma
scaleQn  =  Quantitative:  The result of the test is a numeric value that relates to a continuous numeric scale. Reported either as an integer, a ratio, a real number, or a range. The test result value may optionally contain a relational operator from the set {<=, <, >, >=}. Valid values for a quantitative test are of the form "7", "-7", "7.4", "-7.4", "7.8912", "0.125", "<10", "<10.15", ">12000", 1-10, 1:256
method

Additional Names

short nameNormalized SCT PPP-Rto

Basic Attributes

classCOAG
type1  Laboratory
order vs. observationBoth

Associated Observations

LOINC codes that represent optional associated observation(s) for a clinical observation or laboratory test. A LOINC term may represent a single associated observation or panel containing several associated observations.

History/Usage

test rank2662 of 2000 most commonly performed tests by labs in USA
first released
last updated2.73
last change typeMIN  - change to field other than name

Related Names

Clot
Clottable
COAGULATION
Coagulation time
Hematology
Heme
Normalized SCT
Plas
Platelet poor plasma
Point in time
QNT
Quan
Quant
Quantitative
Random
Rate
Ratios
R-time
Rto
SCT
Silicon dioxide

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.

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