t(6;11)(q27;q23)(MLLT4,MLL) fusion transcript [Presence] in Blood or Tissue by Molecular genetics method 70280-3
LOINC Code
| LOINC code | 70280-3 | ||
|---|---|---|---|
| name | t(6;11)(q27;q23)(MLLT4,MLL) fusion transcript [Presence] in Blood or Tissue by Molecular genetics method | ||
| description | This term is used to identify a leukemia causing chromosomal translocation resulting in a gene fusion between MLLT4 (6q27) and MLL (11q23) genes. The term was created for (but not limited to) DNA Technology's HemaVision HV01-28N kit, a qualitative in vitro diagnostic test for 28 leukemia causing chromosomal alterations including more than 80 breakpoints plus associated mRNA splice variants. Reverse transcription followed by multiplex nested polymerase chain reactions (RT-PCR) and agarose gel electrophoresis are used to identify gene fusions caused by chromosomal translocations, gene deletions or inversions. Testing information is useful for predicting development of the disease and selection of treatment. | ||
| status | ACTIVE | ||
Fully-Specified Name | |||
| component | t(6;11)(q27;q23)(MLLT4,MLL) fusion transcript | ||
| property | Arb = Arbitrary | ||
| time | Pt = Point in time: To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements. | ||
| system | Bld/Tiss Bld = Whole blood Tiss = Tissue, unspecified | ||
| scale | Ord = Ordinal: Ordered categorical responses, e.g., 1+, 2+, 3+; positive, negative; reactive, indeterminate, nonreactive. | ||
| method | Molgen = Molecular Genetics: General class of methods used to detect genetic attributes on a molecular basis including RFL, PCR and other methods. | ||
Additional Names | |||
| short name | t(6;11)(MLLT4,MLL) Bld/T Ql | ||
Basic Attributes | |||
| class | MOLPATH.TRNLOC | ||
| type | 1 Laboratory | ||
| order vs. observation | Both | ||
Associated Observations | |||
LOINC codes that represent optional associated observation(s) for a clinical observation or laboratory test. A LOINC term may represent a single associated observation or panel containing several associated observations. | |||
Member of these Panels | |||
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History/Usage | |||
| first released | |||
| last updated | 2.40 | ||
| last change type | MIN - change to field other than name | ||
Related Names | |||
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