t(17;19)(q22;p13.3)(HLF,TCF3) fusion transcript [Presence] in Blood or Tissue by Molecular genetics method   70288-6

LOINC Code


LOINC code70288-6
namet(17;19)(q22;p13.3)(HLF,TCF3) fusion transcript [Presence] in Blood or Tissue by Molecular genetics method
descriptionThis term is used to identify a leukemia causing chromosomal translocation resulting in a gene fusion between HLF (17q22) and TCF3 (19p13) genes. The term was created for (but not limited to) DNA Technology's HemaVision HV01-28N kit, a qualitative in vitro diagnostic test for 28 leukemia causing chromosomal alterations including more than 80 breakpoints plus associated mRNA splice variants. Reverse transcription followed by multiplex nested polymerase chain reactions (RT-PCR) and agarose gel electrophoresis are used to identify gene fusions caused by chromosomal translocations, gene deletions or inversions. Testing information is useful for predicting development of the disease and selection of treatment.
statusACTIVE

Fully-Specified Name

componentt(17;19)(q22;p13.3)(HLF,TCF3) fusion transcript
propertyArb  =  Arbitrary
timePt  =  Point in time:  To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements.
systemBld/Tiss
    Bld  =  Whole blood
    Tiss  =  Tissue, unspecified
scaleOrd  =  Ordinal:  Ordered categorical responses, e.g., 1+, 2+, 3+; positive, negative; reactive, indeterminate, nonreactive.
methodMolgen  =  Molecular Genetics:  General class of methods used to detect genetic attributes on a molecular basis including RFL, PCR and other methods.

Additional Names

short namet(17;19)(HLF,TCF3) Bld/T Ql

Basic Attributes

classMOLPATH.TRNLOC
type1  Laboratory
order vs. observationBoth

Associated Observations

LOINC codes that represent optional associated observation(s) for a clinical observation or laboratory test. A LOINC term may represent a single associated observation or panel containing several associated observations.

Member of these Panels

72103-5Acute and chronic leukemia fusion transcript panel - Blood or Tissue by Molecular genetics method

History/Usage

first released
last updated2.40
last change typeMIN  - change to field other than name

Related Names

Arbitrary
Blood
DNA
E2A Immunoglobulin enhancer binding factors E12/E47
gene fusion
gene translocation
Genetics
Heredity
Heritable
Immunoglobulin transcription factor 1
Inherited
ITF1
Molecular genetics
Molecular pathology
MOLPATH
MOLPATH.TRANSLOCATION
Ordinal
PCR
Point in time
QL
Qual
Qualitative
Random
RNA
Screen
T prime
t(17
19)(HLF,TCF3)
Tissue
Tissue, unspecified
Transcription factor 3
translocation
WB
Whole blood
Whole blood or Tissue

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.

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