von Willebrand factor (vWf).activity [Units/volume] in Platelet poor plasma by Immunoassay 73978-9
LOINC Code
| LOINC code | 73978-9 | ||
|---|---|---|---|
| name | von Willebrand factor (vWf).activity [Units/volume] in Platelet poor plasma by Immunoassay | ||
| description | Von Willebrand Factor Activity (VWF Activity, vWF:Act) in plasma specimens can be quantitatively determined by immunological methods. This code is created for, but not limited in use to, the submitter's kit, HemosIL Von Willebrand Factor Activity Kit, which determines VWF activity by measuring the increase of turbidity produced by the agglutination of the latex reagent. This assay uses a specific anti-VWF monoclonal antibody directed against the platelet binding site of VWF, glycoprotein Ib receptor, and reacts with the VWF in patient plasma. The degree of agglutination is directly proportional to the activity of VWF in the sample and is determined by measuring the decrease of transmitted light caused by the aggregates. The submitter's lab reports the results in U/mL where U represents "units" rather than the standard meaning of U, which is mmol/Min, a measure of enzyme rates. Additional testing (e.g. ristocetin cofactor assay) may be needed to confirm a diagnosis of von Willebrand disease (VWD). | ||
| status | ACTIVE | ||
Fully-Specified Name | |||
| component | von Willebrand factor.activity | ||
| property | ACnc = Arbitrary Concentration | ||
| time | Pt = Point in time: To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements. | ||
| system | PPP = Platelet poor plasma | ||
| scale | Qn = Quantitative: The result of the test is a numeric value that relates to a continuous numeric scale. Reported either as an integer, a ratio, a real number, or a range. The test result value may optionally contain a relational operator from the set {<=, <, >, >=}. Valid values for a quantitative test are of the form "7", "-7", "7.4", "-7.4", "7.8912", "0.125", "<10", "<10.15", ">12000", 1-10, 1:256 | ||
| method | IA = Immunoassay: Encompasses all immunoassays with a few exceptions, including Immune Blot and Immune Fluorescence, which were created based on historic usage. | ||
Additional Names | |||
| short name | vWf:Ac PPP IA-aCnc | ||
Basic Attributes | |||
| class | COAG | ||
| type | 1 Laboratory | ||
| order vs. observation | Both | ||
| example UCUM units | [arb'U]/mL The Unified Code for Units of Measure (UCUM) is a code system intended to include all units of measures being contemporarily used in international science, engineering, and business (www.unitsofmeasure.org) | ||
| example unit | arb U/mL | ||
Associated Observations | |||
LOINC codes that represent optional associated observation(s) for a clinical observation or laboratory test. A LOINC term may represent a single associated observation or panel containing several associated observations. | |||
History/Usage | |||
| test rank | 8787 of 2000 most commonly performed tests by labs in USA | ||
| first released | |||
| last updated | 2.73 | ||
| last change type | MIN - change to field other than name | ||
| change reason | Renamed Method from "Imm" to "IA" for consistency across classes (approved by Laboratory LOINC Committee 2016 12). | ||
Related Names | |||
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