Breast cancer 10-year risk of distant recurrence score Calculated by Prosigna 76544-6
LOINC Code
LOINC code | 76544-6 | ||
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name | Breast cancer 10-year risk of distant recurrence score Calculated by Prosigna | ||
description | The 10-year breast cancer distant recurrence risk score (also referred to as ROR Score or Risk of Recurrence Score) is a numerical score on a scale of 0 -100 that is calculated using a statistical model that includes: 1) the results from a 50-gene expression assay performed on formalin fixed paraffin embedded breast tumor tissue previously diagnosed as invasive carcinoma; 2) proliferation score; and 3) gross tumor size. The calculated score and information about lymph node status are used together to classify the patient into a risk category for distant breast cancer recurrence at 10 years. This term was created for the Prosigna™ Breast Cancer Prognostic Gene Signature assay, which is intended for use in postmenopausal women with node-negative (Stage I or II) or node-positive (Stage II), hormone receptor-positive (HR+) breast cancer who have undergone surgery and are to be treated with adjuvant endocrine therapy alone. | ||
status | ACTIVE | ||
Fully-Specified Name | |||
component | Breast cancer 10Y risk of distant recurrence score | ||
property | Score | ||
time | Pt = Point in time: To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements. | ||
system | ^Patient | ||
scale | Qn = Quantitative: The result of the test is a numeric value that relates to a continuous numeric scale. Reported either as an integer, a ratio, a real number, or a range. The test result value may optionally contain a relational operator from the set {<=, <, >, >=}. Valid values for a quantitative test are of the form "7", "-7", "7.4", "-7.4", "7.8912", "0.125", "<10", "<10.15", ">12000", 1-10, 1:256 | ||
method | Calculated.Prosigna | ||
Additional Names | |||
short name | Brst ca 10Y dist recur score Prosigna | ||
Basic Attributes | |||
class | MOLPATH | ||
type | 1 Laboratory | ||
order vs. observation | Both | ||
formula (readable) | Calculated using a Cox model that includes coefficients for the gene expression assay results, proliferation score, and gross tumor size. | ||
example UCUM units | {score} The Unified Code for Units of Measure (UCUM) is a code system intended to include all units of measures being contemporarily used in international science, engineering, and business (www.unitsofmeasure.org) | ||
example unit | score | ||
Associated Observations | |||
LOINC codes that represent optional associated observation(s) for a clinical observation or laboratory test. A LOINC term may represent a single associated observation or panel containing several associated observations. | |||
Member of these Panels | |||
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History/Usage | |||
test rank | 17578 of 2000 most commonly performed tests by labs in USA | ||
first released | |||
last updated | 2.73 | ||
last change type | MIN - change to field other than name | ||
change reason | Order_Obs: changed from 'observation' to 'both' to reflect that the LOINC code can also be used as an order code. | ||
Related Names | |||
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