Noninvasive colorectal cancer DNA and occult blood screening [Interpretation] in Stool Narrative   77353-1

LOINC Code


LOINC code77353-1
nameNoninvasive colorectal cancer DNA and occult blood screening [Interpretation] in Stool Narrative
descriptionThis term was created for, but is not limited in use to, Exact Sciences' Cologuard DNA screening test for colorectal cancer. The Cologuard algorithm includes two laboratory procedures performed on a single stool specimen: 1) detection and quantification of fecal occult blood using ELISA; and 2) detection of multiple genetic biomarkers (NDRG4 and BMP3 methylation targets, seven KRAS point mutations, and beta actin as a proxy for the total amount of human DNA in each sample) using magnetic bead based oligonucleotide hybrid capture to isolate the biomarkers followed by quantitative real-time target and signal amplification. The occult blood and genetic biomarker results are subsequently entered into a logistic regression model, and the results from this model are used to calculate a composite score from which the final binary result (positive, negative) is determined. [PMID: 24645800]
statusACTIVE

Fully-Specified Name

componentNoninvasive colorectal cancer DNA+occult blood screening
propertyImp  =  Impression/interpretation of study
timePt  =  Point in time:  To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements.
systemStool  =  Stool = Fecal
scaleNar  =  Narrative:  Text narrative, such as the description of a microscopic part of a surgical papule test.
method

Additional Names

short nameNoninv colon ca DNA+occ bld scrn Stl-Imp

Basic Attributes

classMOLPATH
type1  Laboratory
order vs. observationObservation

Associated Observations

LOINC codes that represent optional associated observation(s) for a clinical observation or laboratory test. A LOINC term may represent a single associated observation or panel containing several associated observations.

Member of these Panels

82956-4HEDIS 2017-2020 Value Set - FIT-DNA
82956-4HEDIS 2017-2020 Value Set - FIT-DNA
82956-4HEDIS 2017-2020 Value Set - FIT-DNA
82956-4HEDIS 2017-2020 Value Set - FIT-DNA

History/Usage

test rank4228 of 2000 most commonly performed tests by labs in USA
first released
last updated2.73
last change typeMIN  - change to field other than name

Related Names

Asympt
Asymptomatic
Bowel movement
Deoxyribonucleic acid
Faecal
Faeces
Fecal
Feces
Impression
Impression/interpretation of study
Impressions
Interp
Interpretation
Molecular pathology
MOLPATH
Narrative
Noninv colon ca DNA+occ bld screen
Occ
Point in time
Random
Report
Scn
Stl
Stool = Fecal

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.

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