Cortisol [Moles/volume] in Serum or Plasma --10 hours post XXX challenge   77935-5

LOINC Code


LOINC code77935-5
nameCortisol [Moles/volume] in Serum or Plasma --10 hours post XXX challenge
descriptionTimed cortisol levels are obtained for adrenocorticotropic hormone challenge tests to assist in diagnosing adrenocortical insufficiency as found in Cushing's syndrome and Addison's disease. There are different types of challenges. ACTH (adrenocorticotropic hormone) stimulation, where cosyntropin (a synthetic form of ACTH) is given, and then blood is sampled for cortisol levels before the bolus, and at specified times after the bolus. The ACTH stimulation directly evaluates adrenal gland function and indirectly evaluates pituitary gland and hypothalamus function. Cortisol levels rise significantly after administration of cosyntropin if the adrenal glands are functioning normally. For the CRH (corticotropin-releasing hormone) stimulation, CRH is given and cortisol and ACTH levels are determined before the injection, at the injection time, and specified times following injection. The CRH stimulation test is used to distinguish Cushings disease from conditions where ACTH is secreted ectopically. For the Dexamethasone suppression (overnight) test (DST), dexamethasone (Decadron) is given and samples for cortisol levels are collected the following morning. The DST differentiates the causes of increased cortisol levels. For the Metyrapone (overnight) stimulation challenge, metyrapone is given with a snack at midnight. Samples for cortisol, 11-deoxycortisol, and ACTH are collected the following morning. The metyrapone stimulation test distinguishes corticotropin-dependent causes (pituitary Cushing's disease and ectopic Cushing's disease) from corticotropin-independent causes (carcinoma of the lung or thyroid) of increased cortisol levels..
statusACTIVE

Fully-Specified Name

componentCortisol^10H post XXX challenge
propertySCnc  =  Substance Concentration
timePt  =  Point in time:  To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements.
systemSer/Plas
    Ser  =  Serum
    Plas  =  Plasma
scaleQn  =  Quantitative:  The result of the test is a numeric value that relates to a continuous numeric scale. Reported either as an integer, a ratio, a real number, or a range. The test result value may optionally contain a relational operator from the set {<=, <, >, >=}. Valid values for a quantitative test are of the form "7", "-7", "7.4", "-7.4", "7.8912", "0.125", "<10", "<10.15", ">12000", 1-10, 1:256
method

Additional Names

short nameCortis 10h p chal SerPl-sCnc

Basic Attributes

classCHAL
type1  Laboratory
order vs. observationObservation
example UCUM unitsnmol/L
The Unified Code for Units of Measure (UCUM) is a code system intended to include all units of measures being contemporarily used in international science, engineering, and business (www.unitsofmeasure.org)
example unitnmol/L

Associated Observations

LOINC codes that represent optional associated observation(s) for a clinical observation or laboratory test. A LOINC term may represent a single associated observation or panel containing several associated observations.

History/Usage

first released
last updated2.58
last change typeMIN  - change to field other than name

Related Names

10h p chal
17-Hydroxycorticosterone
After
CHEMISTRY.CHALLENGE TESTING
Compound F
Coritsol
Cort
F
hydrocortisone
Level
p chal
Pl
Plasma
Plsm
Point in time
PST
QNT
Quan
Quant
Quantitative
Random
SerP
SerPl
SerPlas
Serum
Serum or plasma
SR
Substance concentration

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.

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