Acyl CoA dehydrogenases [Enzymatic activity/mass] in Fibroblast by [9,10-3H] myristate substrate   78360-5

LOINC Code


LOINC code78360-5
nameAcyl CoA dehydrogenases [Enzymatic activity/mass] in Fibroblast by [9,10-3H] myristate substrate
descriptionOne method for diagnosing acyl CoA dehydrogenase deficiencies is fatty acid oxidation analysis in cultured fibroblasts. Using multiple fatty acid substrates with varying carbon chain lengths, such as palmitate (16 carbons) [LOINC: 78358-9] and and myristate (14 carbons) (this term), can help differentiate between disorders such as long-chain acyl CoA dehydrogenase deficiency and medium-chain acyl CoA dehydrogenase deficiency.[PMID: 2109149] Enzyme activity is measured as nanomoles of fatty acid oxidized per hour per milligram of cell protein (nmol FA/h/mg protein). [PMID: 12840153]
statusACTIVE

Fully-Specified Name

componentAcyl CoA dehydrogenases
propertyCCnt  =  Catalytic Content
timePt  =  Point in time:  To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements.
systemFibroblasts
scaleQn  =  Quantitative:  The result of the test is a numeric value that relates to a continuous numeric scale. Reported either as an integer, a ratio, a real number, or a range. The test result value may optionally contain a relational operator from the set {<=, <, >, >=}. Valid values for a quantitative test are of the form "7", "-7", "7.4", "-7.4", "7.8912", "0.125", "<10", "<10.15", ">12000", 1-10, 1:256
method[9,10-3H] myristate substrate

Additional Names

short nameACADs Fib Myristate-cCnt

Basic Attributes

classCHEM
type1  Laboratory
order vs. observationBoth
example UCUM unitsnmol/h/mg{protein}
The Unified Code for Units of Measure (UCUM) is a code system intended to include all units of measures being contemporarily used in international science, engineering, and business (www.unitsofmeasure.org)
example unitnmol/H/mg protein

Associated Observations

LOINC codes that represent optional associated observation(s) for a clinical observation or laboratory test. A LOINC term may represent a single associated observation or panel containing several associated observations.

Member of these Groups

LG30219-6Acyl CoA dehydrogenases|CCnt|Pt|Fibroblasts

Member of these Panels

74533-1Fatty acid oxidation panel - Fibroblast

History/Usage

first released
last updated2.54
last change typeADD  - added

Related Names

ACADs
Catalytic Content
Chemistry
Fib
Fibr
Point in time
QNT
Quan
Quant
Quantitative
Random

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.

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